Hypotensive Effect of a Novel Dihydropyridine with Dual Calcium Channel Blocking and Angiotensin II Antagonistic Properties in a Rat Model

In this study, the effects of this losartan (compound A) on the blood pressure (BP) and the heart rate (HR) of normotensive rats were investigated and compared to losartan, which was used as a positive control. A novel dihydropyridine compound was synthesized by connecting a dihydropyridine nucleus...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Pharmaceutical Sciences 2014-12, Vol.19 (4), p.135
Hauptverfasser:	Imenshahidi, Mohsen, Alipour, Milad, Hadizadeh, Farzin, Motamed-Shariaty, Vahideh Sadat
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium Drug dosages Rodents Variance analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!