Boron neutron capture synovectomy (BNCS) as a potential therapy for rheumatoid arthritis: boron biodistribution study in a model of antigen-induced arthritis in rabbits

Boron neutron capture synovectomy (BNCS) is explored for the treatment of rheumatoid arthritis (RA). The aim of the present study was to perform boron biodistribution studies in a model of antigen-induced arthritis (AIA) in female New Zealand rabbits, with the boron carriers boronophenylalanine (BPA...

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Veröffentlicht in:	Radiation and environmental biophysics 2014-11, Vol.53 (4), p.635-643
Hauptverfasser:	Trivillin, Verónica A., Abramson, David B., Bumaguin, Gaston E., Bruno, Leandro J., Garabalino, Marcela A., Monti Hughes, Andrea, Heber, Elisa M., Feldman, Sara, Schwint, Amanda E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens Antigens - adverse effects Arthritis, Rheumatoid - chemically induced Arthritis, Rheumatoid - therapy Biological and Medical Physics Biophysics Boron Boron - pharmacokinetics Boron - therapeutic use Boron Compounds - pharmacokinetics Boron Neutron Capture Therapy Disease Models, Animal Ecosystems Effects of Radiation/Radiation Protection Environmental Physics Feasibility Studies Female Fructose - analogs & derivatives Fructose - pharmacokinetics Intravenous administration Mass spectrometry Monitoring/Environmental Analysis Neutrons Original Paper Physics Physics and Astronomy Rabbits Rheumatoid arthritis Therapy Tissue Distribution
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