DNA Intercalating RuII Polypyridyl Complexes as Effective Photosensitizers in Photodynamic Therapy

Six substitutionally inert [RuII(bipy)2dppz]2+ derivatives (bipy=2,2′‐bipyridine, dppz=dipyrido[3,2‐a:2′,3′‐c]phenazine) bearing different functional groups on the dppz ligand [NH2 (1), OMe (2), OAc (3), OH (4), CH2OH (5), CH2Cl (6)] were synthesized and studied as potential photosensitizers (PSs) i...

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Veröffentlicht in:	Chemistry : a European journal 2014-10, Vol.20 (44), p.14421-14436
Hauptverfasser:	Mari, Cristina, Pierroz, Vanessa, Rubbiani, Riccardo, Patra, Malay, Hess, Jeannine, Spingler, Bernhard, Oehninger, Luciano, Schur, Julia, Ott, Ingo, Salassa, Luca, Ferrari, Stefano, Gasser, Gilles
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry density functional calculations DNA binding fluorescence microscopy photodynamic therapy singlet oxygen
Online-Zugang:	Volltext
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