Quantiosomes as a Multimodal Nanocarrier for Integrating Bioimaging and Carboplatin Delivery

ABSTRACT Purpose Here we report the development of quantiosomes, niosomes formed from Span 60, cholesterol, and quantum dots (QDs), for achieving sensitive bioimaging and anticancer drug delivery. Methods The nanocarriers were further modified by incorporating soy phosphatidylcholine (SPC), polyethy...

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Veröffentlicht in:	Pharmaceutical research 2014-10, Vol.31 (10), p.2664-2676
Hauptverfasser:	Lin, Chwan-Fwu, Wen, Chih-Jen, Aljuffali, Ibrahim A., Huang, Chun-Lin, Fang, Jia-You
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - administration & dosage Antineoplastic Agents - pharmacokinetics Antineoplastic Agents - pharmacology Biochemistry Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Carboplatin - administration & dosage Carboplatin - pharmacokinetics Carboplatin - pharmacology Cell Line, Tumor Cell Movement - drug effects Cell Survival - drug effects Cholesterol - chemistry Diagnostic Imaging - methods Drug Carriers - chemistry Drug Compounding Drug delivery systems Drug Liberation Drug Screening Assays, Antitumor Female Hexoses - chemistry Liposomes Medical Law Melanoma Melanoma - pathology Mice, Nude Neoplasm Transplantation Optical Imaging - methods Ovarian Neoplasms - pathology Particle Size Pharmaceutical sciences Pharmacology/Toxicology Pharmacy Quantum dots Quantum Dots - chemistry Research Paper Scientific imaging Surface Properties
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