Monitoring Survivin Expression in Cancer: Implications for Prognosis and Therapy

Survivin, a member of the inhibitor of apoptosis protein family, is one of the most cancer-specific proteins identified to date. Survivin expression is low or undetectable in most adult tissues, but, alternatively, is overexpressed in a large number of tumors. This multifunctional protein is recogni...

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Veröffentlicht in:Molecular diagnosis & therapy 2013-12, Vol.17 (6), p.331-342
Hauptverfasser: Guindalini, Rodrigo Santa Cruz, Mathias Machado, Maria Cecília, Garicochea, Bernardo
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Sprache:eng
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