Sensitive Solid-Phase Detection of Donor-Specific Antibodies as an Aid Highly Relevant to Improving Allograft Outcomes

Transplant recipients who have had sensitizing events such as pregnancies, blood transfusions and previous transplants often develop antibodies directed against human leukocyte antigen (HLA)-molecules of the donor tissue. These pre-formed donor-specific antibodies (DSA) represent a high risk of orga...

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Veröffentlicht in:	Molecular diagnosis & therapy 2014-04, Vol.18 (2), p.185-201
Hauptverfasser:	Schlaf, Gerald, Pollok-Kopp, Beatrix, Altermann, Wolfgang W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allografts - immunology Antibody Specificity Antigens Biomedical and Life Sciences Biomedicine Cancer Research Design Enzyme-Linked Immunosorbent Assay Flow Cytometry Graft Rejection - immunology Graft Survival - immunology HLA Antigens - analysis Human Genetics Humans Kidneys Laboratory Medicine Lymphocytes Medical laboratories Molecular Medicine Patients Pharmacotherapy Phenotype Review Article Transplants & implants
Online-Zugang:	Volltext
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