Safety and immunogenicity of WRSd1, a live attenuatedShigella dysenteriaetype 1 vaccine candidate

AmongShigellaserotypesShigella dysenteriaetype 1 produces the most severe disease, including cases of hemolytic-uremic syndrome and pandemic outbreaks. WRSd1 is a liveS. dysenteriae1 strain attenuated by deletion of thevirG(icsA) gene, which encodes a protein that mediates intercellular spread, ands...

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Veröffentlicht in:	Vaccine 2008-06, Vol.26 (26), p.3291
Hauptverfasser:	McKenzie, Robin, Venkatesan, Malabi M, Wolf, Marcia K, Islam, Dilara, Grahek, Shannon, Jones, Andrea M, Bloom, Arlene, Taylor, David N, Hale, Thomas L, Bourgeois, A Louis
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriology Developing countries Displaced persons Fever Hepatitis Immunization Immunogenicity LDCs Nervous system Proteins Toxins Vaccines
Online-Zugang:	Volltext
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