Effectiveness of Clindamycin and Intravenous Immunoglobulin, and Risk of Disease in Contacts, in Invasive Group A Streptococcal Infections

Background. The use of clindamycin and intravenous immunoglobulin (IVIG) in treatment of invasive group A streptococcal (iGAS) infection, and the need for prophylactic antibiotics in close contacts, remains contentious. Controlled trials are unlikely to be conducted, so prospective, observational st...

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Veröffentlicht in:	Clinical infectious diseases 2014-08, Vol.59 (3), p.358-365
Hauptverfasser:	Carapetis, Jonathan R., Jacoby, Peter, Carville, Kylie, Ang, Seong-Jin Joel, Curtis, Nigel, Andrews, Ross
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents - therapeutic use Antibacterial agents Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents ARTICLES AND COMMENTARIES Bacterial diseases Biological and medical sciences Child Child, Preschool Clindamycin - therapeutic use Clinical trials Disease manifestations Disease risk Epidemiology Fasciitis, Necrotizing - drug therapy Fasciitis, Necrotizing - epidemiology Female Human bacterial diseases Humans Immunoglobulins Immunoglobulins, Intravenous - therapeutic use Incidence Infections Infectious diseases Male Medical sciences Middle Aged Mortality Mortality rates Pharmacology. Drug treatments Population Surveillance Preventive medicine Prospective Studies Risk Septic shock Shock, Septic - drug therapy Shock, Septic - epidemiology Staphylococcal infections, streptococcal infections, pneumococcal infections Streptococcal infections Streptococcal Infections - drug therapy Streptococcal Infections - epidemiology Streptococcus Streptococcus - drug effects Streptococcus - isolation & purification Streptococcus infections Survival analysis Victoria - epidemiology Young Adult
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