SPIRONOLACTONE IMPROVES POOR OUTCOME IN PATIENTS WITH NYHA CLASS I OR II CHRONIC HEART FAILURE AND ELEVATED CARDIAC SYMPATHETIC NERVE ACTIVITY
Background Mineralocorticoid antagonist has been shown to decrease the morbidity and mortality in patients with systolic chronic heart failure (CHF) and mild symptoms. Since cardiac sympathetic nerve activity (CSNA) is reported to be associated with poor outcome in patients with CHF, we tried to elu...
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| Veröffentlicht in: | Journal of the American College of Cardiology 2012-03, Vol.59 (13), p.E1173-E1173 |
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| container_end_page | E1173 |
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| container_issue | 13 |
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| container_title | Journal of the American College of Cardiology |
| container_volume | 59 |
| creator | Kondo, Takumi Yamada, Takahisa Morita, Takashi Furukawa, Yoshio Tanaka, Koji Iwasaki, Yusuke Kawasaki, Masato Kuramoto, Yuki Fujimoto, Tadao Yamamoto, Hironori Sengoku, Kaoruko Ozu, Kentaro Fukunami, Masatake |
| description | Background Mineralocorticoid antagonist has been shown to decrease the morbidity and mortality in patients with systolic chronic heart failure (CHF) and mild symptoms. Since cardiac sympathetic nerve activity (CSNA) is reported to be associated with poor outcome in patients with CHF, we tried to elucidate the relation between the efficacy of spironolactone and CSNA in CHF patients with NYHA class I or II. |
| doi_str_mv | 10.1016/S0735-1097(12)61174-7 |
| format | Article |
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Since cardiac sympathetic nerve activity (CSNA) is reported to be associated with poor outcome in patients with CHF, we tried to elucidate the relation between the efficacy of spironolactone and CSNA in CHF patients with NYHA class I or II.</description><subject>Cardiology</subject><subject>Cardiovascular</subject><subject>Clinical outcomes</subject><subject>Heart failure</subject><subject>Internal Medicine</subject><subject>Transplants & implants</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqFkN1q2zAYQM3YYFm3RxgIdrNduNXnP0U3G0JRa4FjB1vJyJWwZRncZUlntYO-RJ-5SlI22M2uBOJ8R_pOEHwEfAkYsqsGkzgNAVPyGaIvGQBJQvIqmEGazsM4peR1MPuDvA3eOXeLMc7mQGfBU7OSdVVWBeOqKgWSy1VdbUSDVlVVo2qteLX0tyVaMSVFqRr0XaoclducIV6wpkESeVBKxHPvkRzlgtUKXTNZrGuBWLlAohAbpsQCcVYvJOOo2S69LhfK46WoNx7jSm6k2r4P3gztztkPL-dFsL4WiudhUd1IzorQwDxNwj5tYcg6i4FC2vfUZqbrLGSYxnGS2YwkAwVsYJgPxNBu6FraYkpJbFtLo2SIL4JPZ-_ddPj1YN29vj08THv_pIY08a0iHCeeSs-UmQ7OTXbQd9P4s50eNWB9TK9P6fWxq4ZIn9Jr4ue-neesX-H3aCftzGj3xvbjZM297g_jfw1f_zGY3bgfTbv7YR-t-_tZ7SKNz5KjA6KTgcTPvfaUQg</recordid><startdate>20120327</startdate><enddate>20120327</enddate><creator>Kondo, Takumi</creator><creator>Yamada, Takahisa</creator><creator>Morita, Takashi</creator><creator>Furukawa, Yoshio</creator><creator>Tanaka, Koji</creator><creator>Iwasaki, Yusuke</creator><creator>Kawasaki, Masato</creator><creator>Kuramoto, Yuki</creator><creator>Fujimoto, Tadao</creator><creator>Yamamoto, Hironori</creator><creator>Sengoku, Kaoruko</creator><creator>Ozu, Kentaro</creator><creator>Fukunami, Masatake</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>20120327</creationdate><title>SPIRONOLACTONE IMPROVES POOR OUTCOME IN PATIENTS WITH NYHA CLASS I OR II CHRONIC HEART FAILURE AND ELEVATED CARDIAC SYMPATHETIC NERVE ACTIVITY</title><author>Kondo, Takumi ; Yamada, Takahisa ; Morita, Takashi ; Furukawa, Yoshio ; Tanaka, Koji ; Iwasaki, Yusuke ; Kawasaki, Masato ; Kuramoto, Yuki ; Fujimoto, Tadao ; Yamamoto, Hironori ; Sengoku, Kaoruko ; Ozu, Kentaro ; Fukunami, Masatake</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1854-d5a1f6be01915dd9e6cbbe16093346e674f910c1f8f7c9bfba9a09973eae924f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Cardiology</topic><topic>Cardiovascular</topic><topic>Clinical outcomes</topic><topic>Heart failure</topic><topic>Internal Medicine</topic><topic>Transplants & implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kondo, Takumi</creatorcontrib><creatorcontrib>Yamada, Takahisa</creatorcontrib><creatorcontrib>Morita, Takashi</creatorcontrib><creatorcontrib>Furukawa, Yoshio</creatorcontrib><creatorcontrib>Tanaka, Koji</creatorcontrib><creatorcontrib>Iwasaki, Yusuke</creatorcontrib><creatorcontrib>Kawasaki, Masato</creatorcontrib><creatorcontrib>Kuramoto, Yuki</creatorcontrib><creatorcontrib>Fujimoto, Tadao</creatorcontrib><creatorcontrib>Yamamoto, Hironori</creatorcontrib><creatorcontrib>Sengoku, Kaoruko</creatorcontrib><creatorcontrib>Ozu, Kentaro</creatorcontrib><creatorcontrib>Fukunami, Masatake</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kondo, Takumi</au><au>Yamada, Takahisa</au><au>Morita, Takashi</au><au>Furukawa, Yoshio</au><au>Tanaka, Koji</au><au>Iwasaki, Yusuke</au><au>Kawasaki, Masato</au><au>Kuramoto, Yuki</au><au>Fujimoto, Tadao</au><au>Yamamoto, Hironori</au><au>Sengoku, Kaoruko</au><au>Ozu, Kentaro</au><au>Fukunami, Masatake</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>SPIRONOLACTONE IMPROVES POOR OUTCOME IN PATIENTS WITH NYHA CLASS I OR II CHRONIC HEART FAILURE AND ELEVATED CARDIAC SYMPATHETIC NERVE ACTIVITY</atitle><jtitle>Journal of the American College of Cardiology</jtitle><date>2012-03-27</date><risdate>2012</risdate><volume>59</volume><issue>13</issue><spage>E1173</spage><epage>E1173</epage><pages>E1173-E1173</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><abstract>Background Mineralocorticoid antagonist has been shown to decrease the morbidity and mortality in patients with systolic chronic heart failure (CHF) and mild symptoms. 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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Access via ScienceDirect (Elsevier); Alma/SFX Local Collection |
| subjects | Cardiology Cardiovascular Clinical outcomes Heart failure Internal Medicine Transplants & implants |
| title | SPIRONOLACTONE IMPROVES POOR OUTCOME IN PATIENTS WITH NYHA CLASS I OR II CHRONIC HEART FAILURE AND ELEVATED CARDIAC SYMPATHETIC NERVE ACTIVITY |
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