Human papillomavirus-like particles mediate functional delivery of plasmid DNA to antigen presenting cellsin vivo

Because recombinant empty viral capsids are potentially attractive vectors for gene therapy, here we examined the ability of human papillomavirus (HPV) virus-like particles (VLPs) to mediate delivery and expression of DNA plasmidsin vitroandin vivo. VLP-mediated delivery and expression of a GFP repo...

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Veröffentlicht in:	Vaccine 2007-04, Vol.25 (17), p.3270
Hauptverfasser:	Malboeuf, Christine M, Simon, David AL, Lee, Young-Eun Ellen, Lankes, Heather A, Dewhurst, Stephen, Frelinger, John G, Rose, Robert C
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Atoms & subatomic particles Cell cycle Deoxyribonucleic acid Disease DNA Gene expression Human papillomavirus Immunization Plasmids Prophylaxis Proteins RNA polymerase Vaccines
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