Antibodies to the pneumococcal surface protein A, PspA, can be produced in splenectomized mice and can protect splenectomized mice from infection withStreptococcus pneumoniae

Asplenic individuals have increased susceptibility to septicemia caused by encapsulated bacteria.Streptococcus pneumoniae, a pathogen carried in the nasal passages of many humans without complication, is responsible for a large proportion of infections seen in asplenic individuals. Our studies have...

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Veröffentlicht in:Vaccine 2005-07, Vol.23 (33), p.4257
Hauptverfasser: Coats, Mamie T, Benjamin, WH, Hollingshead, SK, Briles, DE
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Sprache:eng
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