Oligomannurarate sulfate sensitizes cancer cells to doxorubicin by inhibiting atypical activation of NF-[kappa]B via targeting of Mre11

Aberrant regulation of nuclear factor kappa B (NF-[kappa]B) transcription factor is involved in cancer development, progression and resistance to chemotherapy. JG3, a marine-derived oligomannurarate sulfate, was reported as a heparanase and NF-[kappa]B inhibitor to significantly block tumor growth a...

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Veröffentlicht in:	International journal of cancer 2012-01, Vol.130 (2), p.467
Hauptverfasser:	Zhang, Jing, Xin, Xianliang, Chen, Qin, Xie, Zuoquan, Gui, Min, Chen, Yi, Lin, Liping, Feng, Jianming, Li, Qiuning, Ding, Jian, Geng, Meiyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Medical research
Online-Zugang:	Volltext
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