Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma
The primary cilium acts as a cellular antenna, transducing diverse signaling pathways, and recent evidence suggests that primary cilia are important in development and cancer. However, a role for cilia in normal muscle development and rhabdomyosarcoma (RMS) has not been explored. Here we implicate p...
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Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 2014-06, Vol.111 (25), p.9151-9156 |
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Sprache: | eng |
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