Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma

The primary cilium acts as a cellular antenna, transducing diverse signaling pathways, and recent evidence suggests that primary cilia are important in development and cancer. However, a role for cilia in normal muscle development and rhabdomyosarcoma (RMS) has not been explored. Here we implicate p...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2014-06, Vol.111 (25), p.9151-9156
Hauptverfasser: Fu, Wenxiang, Asp, Patrik, Canter, Brian, Dynlacht, Brian David
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Sprache:eng
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