The impact of concurrent granulocyte–macrophage colony-stimulating factor on quality of life in head and neck cancer patients: results of the randomized, placebo-controlled Radiation Therapy Oncology Group 9901 trial

Purpose The Radiation Therapy Oncology Group (RTOG) conducted a randomized, placebo-controlled trial evaluating the efficacy of GM-CSF in reducing mucosal injury and symptom burden from curative radiotherapy for head and neck (H&N) cancer. Methods Eligible patients with H&N cancer receiving...

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Veröffentlicht in:	Quality of life research 2014-08, Vol.23 (6), p.1841-1858
Hauptverfasser:	Hoffman, Karen E., Pugh, Stephanie L., James, Jennifer L., Scarantino, Charles, Movsas, Benjamin, Valicenti, Richard K., Fortin, Andre, Pollock, JonDavid, Kim, Harold, Brachman, David G., Berk, Lawrence B., Bruner, Deborah Watkins, Kachnic, Lisa A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Canada Cancer therapies Chemotherapy Cost of Illness Disease models Double-Blind Method Drug dosages Female Granulocyte-Macrophage Colony-Stimulating Factor - adverse effects Granulocyte-Macrophage Colony-Stimulating Factor - therapeutic use Head Head & neck cancer Head and neck neoplasms Head and Neck Neoplasms - psychology Head and Neck Neoplasms - radiotherapy Humans Male Medicine Medicine & Public Health Middle Aged Mucositis Oncology Pain Patient Outcome Assessment Patients Placebos Public Health Quality of Life Quality of Life Research Questionnaires Radiation Injuries - prevention & control Radiation therapy Radiation-Protective Agents - adverse effects Radiation-Protective Agents - therapeutic use Radiotherapy Socioeconomic Factors Sociology Statistical median Surveys and Questionnaires Symptoms United States
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