Towards Structural Systems Pharmacology to Study Complex Diseases and Personalized Medicine: e1003554

Genome-Wide Association Studies (GWAS), whole genome sequencing, and high-throughput omics techniques have generated vast amounts of genotypic and molecular phenotypic data. However, these data have not yet been fully explored to improve the effectiveness and efficiency of drug discovery, which cont...

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Veröffentlicht in:	PLoS computational biology 2014-05, Vol.10 (5)
Hauptverfasser:	Xie, Lei, Ge, Xiaoxia, Tan, Hepan, Xie, Li, Zhang, Yinliang, Hart, Thomas, Yang, Xiaowei, Bourne, Philip E
Format:	Artikel
Sprache:	eng
Schlagworte:	Disease Environmental factors Epigenetics Genes Genomes Genomics Pharmacology Precision medicine Proteins Signal transduction Statistical models Studies
Online-Zugang:	Volltext
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