A case of ovarian endometrioid adenofibroma of borderline malignancy: Evidence for estrogen-producing tumor
A case of ovarian endometrioid adenofibroma of borderline malignancy with an increased serum estradiol level, which rapidly disappeared after removal of the tumor, is reported. Vaginal cytologic analysis showed estrogenic effects, and endometrial cystic glandular hyperplasia was thought to be the re...
Gespeichert in:
Veröffentlicht in: | International journal of clinical oncology 1998-02, Vol.3 (1), p.41-43 |
---|---|
Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 43 |
---|---|
container_issue | 1 |
container_start_page | 41 |
container_title | International journal of clinical oncology |
container_volume | 3 |
creator | Miyagi, Etsuko Hirahara, Fumiki Inayama, Yoshiaki Gorai, Itsuo Yamaguchi, Hajime Nakazawa, Tsuneo Nagashima, Yoji Nakatani, Yukio Minaguchi, Hiroshi Kitamura, Hitoshi |
description | A case of ovarian endometrioid adenofibroma of borderline malignancy with an increased serum estradiol level, which rapidly disappeared after removal of the tumor, is reported. Vaginal cytologic analysis showed estrogenic effects, and endometrial cystic glandular hyperplasia was thought to be the reason for genital bleeding. To determine the origin of estradiol production in the tumor, stromal cells were enzymatically isolated from the tumor and cultured in vitro. Estradiol levels in the cultured media increased in parallel with cell growth. This is the first report showing estrogen secretion from stromal cells in an ovarian endometrioid adenofibroma.[PUBLICATION ABSTRACT] |
doi_str_mv | 10.1007/BF02490101 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1530407238</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3319745361</sourcerecordid><originalsourceid>FETCH-LOGICAL-c160t-79e0e18ffd4dd9237b9f7d7ccbaf4392d0621eb233976d6cca2f9146157d4d3b3</originalsourceid><addsrcrecordid>eNpFkE9LAzEUxIMoWKsXP0HAm7Cal-wmjbcqrQoFL3pesvlTUrtJTXYL_famVPD05vCbmccgdAvkAQgRj89LQmtJgMAZmkDNRCWEoOdFsxoqyWlzia5y3hACgjd0gr7nWKtscXQ47lXyKmAbTOztkHz0BitjQ3S-S7FXR6iLydi09cHiXm39OqigD094sfcF1Ba7mLDNQ4prG6pdimbUPqzxMPYxXaMLp7bZ3vzdKfpaLj5f3qrVx-v7y3xVaeBkqIS0xMLMOVMbIykTnXTCCK075WomqSGcgu0oY1Jww7VW1EmoOTSiOFjHpujulFv6f8byTbuJYwqlsoWGkZoIymaFuj9ROsWck3XtLvlepUMLpD2O2f6PyX4BTetn8w</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1530407238</pqid></control><display><type>article</type><title>A case of ovarian endometrioid adenofibroma of borderline malignancy: Evidence for estrogen-producing tumor</title><source>Springer Nature - Complete Springer Journals</source><creator>Miyagi, Etsuko ; Hirahara, Fumiki ; Inayama, Yoshiaki ; Gorai, Itsuo ; Yamaguchi, Hajime ; Nakazawa, Tsuneo ; Nagashima, Yoji ; Nakatani, Yukio ; Minaguchi, Hiroshi ; Kitamura, Hitoshi</creator><creatorcontrib>Miyagi, Etsuko ; Hirahara, Fumiki ; Inayama, Yoshiaki ; Gorai, Itsuo ; Yamaguchi, Hajime ; Nakazawa, Tsuneo ; Nagashima, Yoji ; Nakatani, Yukio ; Minaguchi, Hiroshi ; Kitamura, Hitoshi</creatorcontrib><description>A case of ovarian endometrioid adenofibroma of borderline malignancy with an increased serum estradiol level, which rapidly disappeared after removal of the tumor, is reported. Vaginal cytologic analysis showed estrogenic effects, and endometrial cystic glandular hyperplasia was thought to be the reason for genital bleeding. To determine the origin of estradiol production in the tumor, stromal cells were enzymatically isolated from the tumor and cultured in vitro. Estradiol levels in the cultured media increased in parallel with cell growth. This is the first report showing estrogen secretion from stromal cells in an ovarian endometrioid adenofibroma.[PUBLICATION ABSTRACT]</description><identifier>ISSN: 1341-9625</identifier><identifier>EISSN: 1437-7772</identifier><identifier>DOI: 10.1007/BF02490101</identifier><language>eng</language><publisher>Tokyo: Springer Nature B.V</publisher><subject>Estrogens ; Ovarian cancer</subject><ispartof>International journal of clinical oncology, 1998-02, Vol.3 (1), p.41-43</ispartof><rights>The Japan Society of Clinical Oncology/Churchill Livingstone Japan 1998</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c160t-79e0e18ffd4dd9237b9f7d7ccbaf4392d0621eb233976d6cca2f9146157d4d3b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids></links><search><creatorcontrib>Miyagi, Etsuko</creatorcontrib><creatorcontrib>Hirahara, Fumiki</creatorcontrib><creatorcontrib>Inayama, Yoshiaki</creatorcontrib><creatorcontrib>Gorai, Itsuo</creatorcontrib><creatorcontrib>Yamaguchi, Hajime</creatorcontrib><creatorcontrib>Nakazawa, Tsuneo</creatorcontrib><creatorcontrib>Nagashima, Yoji</creatorcontrib><creatorcontrib>Nakatani, Yukio</creatorcontrib><creatorcontrib>Minaguchi, Hiroshi</creatorcontrib><creatorcontrib>Kitamura, Hitoshi</creatorcontrib><title>A case of ovarian endometrioid adenofibroma of borderline malignancy: Evidence for estrogen-producing tumor</title><title>International journal of clinical oncology</title><description>A case of ovarian endometrioid adenofibroma of borderline malignancy with an increased serum estradiol level, which rapidly disappeared after removal of the tumor, is reported. Vaginal cytologic analysis showed estrogenic effects, and endometrial cystic glandular hyperplasia was thought to be the reason for genital bleeding. To determine the origin of estradiol production in the tumor, stromal cells were enzymatically isolated from the tumor and cultured in vitro. Estradiol levels in the cultured media increased in parallel with cell growth. This is the first report showing estrogen secretion from stromal cells in an ovarian endometrioid adenofibroma.[PUBLICATION ABSTRACT]</description><subject>Estrogens</subject><subject>Ovarian cancer</subject><issn>1341-9625</issn><issn>1437-7772</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpFkE9LAzEUxIMoWKsXP0HAm7Cal-wmjbcqrQoFL3pesvlTUrtJTXYL_famVPD05vCbmccgdAvkAQgRj89LQmtJgMAZmkDNRCWEoOdFsxoqyWlzia5y3hACgjd0gr7nWKtscXQ47lXyKmAbTOztkHz0BitjQ3S-S7FXR6iLydi09cHiXm39OqigD094sfcF1Ba7mLDNQ4prG6pdimbUPqzxMPYxXaMLp7bZ3vzdKfpaLj5f3qrVx-v7y3xVaeBkqIS0xMLMOVMbIykTnXTCCK075WomqSGcgu0oY1Jww7VW1EmoOTSiOFjHpujulFv6f8byTbuJYwqlsoWGkZoIymaFuj9ROsWck3XtLvlepUMLpD2O2f6PyX4BTetn8w</recordid><startdate>19980201</startdate><enddate>19980201</enddate><creator>Miyagi, Etsuko</creator><creator>Hirahara, Fumiki</creator><creator>Inayama, Yoshiaki</creator><creator>Gorai, Itsuo</creator><creator>Yamaguchi, Hajime</creator><creator>Nakazawa, Tsuneo</creator><creator>Nagashima, Yoji</creator><creator>Nakatani, Yukio</creator><creator>Minaguchi, Hiroshi</creator><creator>Kitamura, Hitoshi</creator><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>19980201</creationdate><title>A case of ovarian endometrioid adenofibroma of borderline malignancy: Evidence for estrogen-producing tumor</title><author>Miyagi, Etsuko ; Hirahara, Fumiki ; Inayama, Yoshiaki ; Gorai, Itsuo ; Yamaguchi, Hajime ; Nakazawa, Tsuneo ; Nagashima, Yoji ; Nakatani, Yukio ; Minaguchi, Hiroshi ; Kitamura, Hitoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c160t-79e0e18ffd4dd9237b9f7d7ccbaf4392d0621eb233976d6cca2f9146157d4d3b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Estrogens</topic><topic>Ovarian cancer</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Miyagi, Etsuko</creatorcontrib><creatorcontrib>Hirahara, Fumiki</creatorcontrib><creatorcontrib>Inayama, Yoshiaki</creatorcontrib><creatorcontrib>Gorai, Itsuo</creatorcontrib><creatorcontrib>Yamaguchi, Hajime</creatorcontrib><creatorcontrib>Nakazawa, Tsuneo</creatorcontrib><creatorcontrib>Nagashima, Yoji</creatorcontrib><creatorcontrib>Nakatani, Yukio</creatorcontrib><creatorcontrib>Minaguchi, Hiroshi</creatorcontrib><creatorcontrib>Kitamura, Hitoshi</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>International journal of clinical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Miyagi, Etsuko</au><au>Hirahara, Fumiki</au><au>Inayama, Yoshiaki</au><au>Gorai, Itsuo</au><au>Yamaguchi, Hajime</au><au>Nakazawa, Tsuneo</au><au>Nagashima, Yoji</au><au>Nakatani, Yukio</au><au>Minaguchi, Hiroshi</au><au>Kitamura, Hitoshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A case of ovarian endometrioid adenofibroma of borderline malignancy: Evidence for estrogen-producing tumor</atitle><jtitle>International journal of clinical oncology</jtitle><date>1998-02-01</date><risdate>1998</risdate><volume>3</volume><issue>1</issue><spage>41</spage><epage>43</epage><pages>41-43</pages><issn>1341-9625</issn><eissn>1437-7772</eissn><abstract>A case of ovarian endometrioid adenofibroma of borderline malignancy with an increased serum estradiol level, which rapidly disappeared after removal of the tumor, is reported. Vaginal cytologic analysis showed estrogenic effects, and endometrial cystic glandular hyperplasia was thought to be the reason for genital bleeding. To determine the origin of estradiol production in the tumor, stromal cells were enzymatically isolated from the tumor and cultured in vitro. Estradiol levels in the cultured media increased in parallel with cell growth. This is the first report showing estrogen secretion from stromal cells in an ovarian endometrioid adenofibroma.[PUBLICATION ABSTRACT]</abstract><cop>Tokyo</cop><pub>Springer Nature B.V</pub><doi>10.1007/BF02490101</doi><tpages>3</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1341-9625 |
ispartof | International journal of clinical oncology, 1998-02, Vol.3 (1), p.41-43 |
issn | 1341-9625 1437-7772 |
language | eng |
recordid | cdi_proquest_journals_1530407238 |
source | Springer Nature - Complete Springer Journals |
subjects | Estrogens Ovarian cancer |
title | A case of ovarian endometrioid adenofibroma of borderline malignancy: Evidence for estrogen-producing tumor |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-23T04%3A59%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20case%20of%20ovarian%20endometrioid%20adenofibroma%20of%20borderline%20malignancy:%20Evidence%20for%20estrogen-producing%20tumor&rft.jtitle=International%20journal%20of%20clinical%20oncology&rft.au=Miyagi,%20Etsuko&rft.date=1998-02-01&rft.volume=3&rft.issue=1&rft.spage=41&rft.epage=43&rft.pages=41-43&rft.issn=1341-9625&rft.eissn=1437-7772&rft_id=info:doi/10.1007/BF02490101&rft_dat=%3Cproquest_cross%3E3319745361%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1530407238&rft_id=info:pmid/&rfr_iscdi=true |