Bruton tyrosine kinase mediatesTLR9-dependent human dendritic cell activation

Background Bruton tyrosine kinase (BTK) plays an essential role in various biologic functions of different cell types. Mutations in BTK lead to X-linked agammaglobulinemia (XLA) in humans. BTK was recently linked to the innate immune system, in particular, the Toll-like receptor (TLR) pathway; howev...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2014-06, Vol.133 (6), p.1644
Hauptverfasser:	Lougaris, Vassilios, Baronio, Manuela, Vitali, Massimiliano, Tampella, Giacomo, Cattalini, Marco, Tassone, Laura, Soresina, Annarosa, Badolato, Raffaele, Plebani, Alessandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical research Cell culture Cytokines Flow cytometry Immune system Life sciences Patients Software
Online-Zugang:	Volltext
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