(+)-Sparteine-Mediated Substitution of o-Benzyl-N-pivaloylaniline with Ketones

The (+)‐sparteine‐mediated lithiation–substitution of o‐benzyl‐N‐pivaloylaniline with various ketones was investigated. The obtained highly enantioenriched tertiary alcohols were used for the synthesis of alkenyl‐substituted products 12 and 13 as well as 3,3,4‐trisubstituted tetrahydroquinoline deri...

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Veröffentlicht in:	European journal of organic chemistry 2014-06, Vol.2014 (16), p.3460-3467
Hauptverfasser:	Ko, Yi Kyung, Im, Chan, Do, Junghwan, Park, Yong Sun
Format:	Artikel
Sprache:	eng
Schlagworte:	Asymmetric synthesis Electrophilic substitution Lithiation Michael addition Synthetic methods
Online-Zugang:	Volltext
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