Synthesis, surface and biological properties of sodium N‐acyl isoleucines

Mixture of fatty acids obtained from coconut, palm kernel, palm, jatropha, karanja, Sterculia foetida, and high oleic sunflower oils were used for the preparation of sodium N‐acyl isoleucines (NaNAIle) via Schotten–Baumann reaction except castor oil which was prepared in thermal condensation in good...

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Veröffentlicht in:European journal of lipid science and technology 2014-02, Vol.116 (2), p.193-206
Hauptverfasser: Sreenu, Madhumanchi, Rao, Bhamidipati V. S. K, Prasad, Rachapudi Badari Narayana, Sujitha, Pombala, Chityala, Ganesh Kumar
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container_end_page 206
container_issue 2
container_start_page 193
container_title European journal of lipid science and technology
container_volume 116
creator Sreenu, Madhumanchi
Rao, Bhamidipati V. S. K
Prasad, Rachapudi Badari Narayana
Sujitha, Pombala
Chityala, Ganesh Kumar
description Mixture of fatty acids obtained from coconut, palm kernel, palm, jatropha, karanja, Sterculia foetida, and high oleic sunflower oils were used for the preparation of sodium N‐acyl isoleucines (NaNAIle) via Schotten–Baumann reaction except castor oil which was prepared in thermal condensation in good yields. The products were characterized by chromatographic and spectral techniques. Surface active properties such as surface tension, wetting, foaming characteristics, emulsion stability, calcium tolerance, and micellization properties were evaluated for all the synthesized products. The results showed that all the products exhibited superior surface active properties like critical micelle concentration (CMC) and emulsion stability when compared to the commercial surfactant, sodium lauryl sulphate (SLS). The NaNAIle also exhibited promising cytotoxicity against human cancer cell lines except 3 and 5. 5, 6, and 8 showed antimicrobial activity against Gram‐positive and Gram‐negative bacteria. 1, 2, 7, and 8 exhibited good antioxidant properties.
doi_str_mv 10.1002/ejlt.201300189
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source Wiley Blackwell Journals
subjects Antibacterial activities
antimicrobial properties
antioxidant activity
Antioxidants
bacteria
calcium
castor oil
coconuts
Cytotoxicity
fatty acids
foaming
Jatropha
Mixture of fatty acids
seeds
Sodium
Sterculia
sunflower oil
Surface active properties
surface tension
title Synthesis, surface and biological properties of sodium N‐acyl isoleucines
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