Prevalence of acquired AmpC [beta]-lactamases in Enterobacteriaceae lacking inducible chromosomal ampC genes at a Spanish hospital from 1999 to 2007

Clin Microbiol Infect 2010; 16: 472-476 In 2007, a significant increase in acquired ampC genes in Enterobacteriaceae from 0.06% in 1999 to 1.3% was observed. Proteus mirabilis showed the highest prevalence (0.95%) and CMY-2 was the most prevalent AmpC enzyme (66.7%). Other enzymes such as CMY-4, DHA...

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Veröffentlicht in:Clinical microbiology and infection 2010-05, Vol.16 (5), p.472
Hauptverfasser: Mata, C, Miro, E, Rivera, A, Mirelis, B, Coll, P, Navarro, F
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Miro, E
Rivera, A
Mirelis, B
Coll, P
Navarro, F
description Clin Microbiol Infect 2010; 16: 472-476 In 2007, a significant increase in acquired ampC genes in Enterobacteriaceae from 0.06% in 1999 to 1.3% was observed. Proteus mirabilis showed the highest prevalence (0.95%) and CMY-2 was the most prevalent AmpC enzyme (66.7%). Other enzymes such as CMY-4, DHA-1, ACC-1, and three new enzymes called CMY-25, CMY-27 and CMY-40 were detected. Seven out of the 117 isolates (6%) also produced an extended-spectrum [beta]-lactamase. As acquired AmpC enzymes are likely to become a serious public health issue worldwide, close surveillance is necessary to curb their spread. [PUBLICATION ABSTRACT]
doi_str_mv 10.1111/j.1469-0691.2009.02864.x
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source Wiley Online Library Journals Frontfile Complete; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Beta
Enzymes
Genes
title Prevalence of acquired AmpC [beta]-lactamases in Enterobacteriaceae lacking inducible chromosomal ampC genes at a Spanish hospital from 1999 to 2007
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