Neuronal and Astroglial TGF[beta]-Smad3 Signaling Pathways Differentially Regulate Dendrite Growth and Synaptogenesis

To address the role of the transforming growth factor beta (TGF[beta])-Smad3 signaling pathway in dendrite growth and associated synaptogenesis, we used small inhibitory RNA to knockdown the Smad3 gene in either cultured neurons and or primary astrocytes. We found that TGF[beta]1 treatment of primar...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Neuromolecular medicine 2014-06, Vol.16 (2), p.457
Hauptverfasser:	Yu, Chuan-yong, Gui, Wei, He, Hui-yan, Wang, Xiao-shan, Zuo, Jian, Huang, Lin, Zhou, Nong, Wang, Kai, Wang, Yu
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!