Muscarinic M^sub 3^ Receptors Contribute to Allergen-Induced Airway Remodeling in Mice

This paper aims to study the contribution of the muscarinic M3 receptor to allergen-induced remodeling using muscarinic M3 receptor subtype-deficient (M3R^sup -/-^) mice. Wild-type (WT), M1R^sup -/-^, and M2R^sup -/-^ mice were used as controls. C57Bl/6 mice were sensitized and challenged with ovalb...

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Veröffentlicht in:	American journal of respiratory cell and molecular biology 2014-04, Vol.50 (4), p.690
Hauptverfasser:	Kistemaker, Loes E M, Bos, Sophie T, Mudde, Willemieke M, Hylkema, Machteld N, Hiemstra, Pieter S, Wess, Jürgen, Meurs, Herman, Kerstjens, Huib A M, Gosens, Reinoud
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosols Animals Asthma Gene expression Hypotheses Muscular system Rodents Smooth muscle Studies
Online-Zugang:	Volltext
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