6[beta]-Naltrexol, a Peripherally Selective Opioid Antagonist that Inhibits Morphine-Induced Slowing of Gastrointestinal Transit: An Exploratory Study

Objective. Opioid-induced constipation is a frequent side effect of opioid pain therapy due to opioid effects on the enteric nervous system, including gastric emptying and fluid absorption. The current exploratory studies were conducted to determine whether the neutral opioid antagonist 6[beta]-nalt...

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Veröffentlicht in:Pain medicine (Malden, Mass.) Mass.), 2011-12, Vol.12 (12), p.1727
Hauptverfasser: Yancey-Wrona, Janet, Dallaire, Brian, Bilsky, Edward, Bath, Brad, Burkart, John, Webster, Lynn, Magiera, Dan, Yang, Xiaoxia, Phelps, Mitch, Sadee, Wolfgang
Format: Artikel
Sprache:eng
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