Rapid early innate control of hepatitis C virus during IFN-[alpha] treatment compromises adaptive CD4+ T-cell immunity

The ability to control HCV with IFN-[alpha]-based treatments provides an opportunity in humans to study how the rate of viral clearance in vivo impinges on the development of antiviral responses. Ex vivo (IFN-[gamma]-producing) and cultured antiviral CD4+ T cells, serum cytokines, and viral loads we...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	European journal of immunology 2012-09, Vol.42 (9), p.2383
Hauptverfasser:	Pembroke, Tom, Rees, Ian, Gallagher, Kathleen, Jones, Emma, Mizen, Paul, Navruzov, Timur, Freedman, Andrew, Fielding, Ceri, Humphreys, Ian R, Wang, Eddie C Y, Gallimore, Awen M, Godkin, Andrew
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug therapy T cell receptors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!