Apomorphine treatment in Alzheimer mice promoting amyloid-[beta] degradation

Objective: Intracellular amyloid [beta]-protein (A[beta]) contributes to neurodegeneration in Alzheimer disease (AD). Apomorphine (APO) is a dopamine receptor agonist for Parkinson disease and also protects against oxidative stress. Efficacy of APO for an AD mouse model and effects of APO on cell cu...

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Veröffentlicht in:	Annals of neurology 2011-02, Vol.69 (2), p.248
Hauptverfasser:	Himeno, Eri, Ohyagi, Yasumasa, Ma, Linqing, Nakamura, Norimichi, Miyoshi, Katsue, Sakae, Nobutaka, Motomura, Kyoko, Soejima, Naoko, Yamasaki, Ryo, Hashimoto, Tetsuya, Tabira, Takeshi, M. LaFerla, Frank, Kira, Jun-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Medical research Mutation Oxidative stress Rodents
Online-Zugang:	Volltext
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