Kinetic differences in the induction of interferon stimulated genes by interferon-[alpha] and interleukin 28B are altered by infection with hepatitis C virus

Several genome-wide association studies (GWAS) have identified a genetic polymorphism associated with the gene locus for interleukin 28B (IL28B), a type III interferon (IFN), as a major predictor of clinical outcome in hepatitis C. Antiviral effects of the type III IFN family have previously been sh...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2014-04, Vol.59 (4), p.1250
Hauptverfasser:	Jilg, Nikolaus, Lin, Wenyu, Hong, Jian, Schaefer, Esperance A, Wolski, David, Meixong, James, Goto, Kaku, Brisac, Cynthia, Chusri, Pattranuch, Fusco, Dahlene N, Chevaliez, Stephane, Luther, Jay, Kumthip, Kattareeya, Urban, Thomas J, Peng, Lee F, Lauer, Georg M, Chung, Raymond T
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene expression Hepatitis Hepatitis C Hepatology Immune system Interferon
Online-Zugang:	Volltext
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