Platelet Reactivity After Clopidogrel Treatment Assessed With Point-of-Care Analysis and Early Drug-Eluting Stent Thrombosis

Objectives The aim of this prospective trial was to assess whether platelet reactivity to clopidogrel assessed with multiple electrode platelet aggregometry (MEA) correlates with the risk of early drug-eluting stent thrombosis (ST). Background Studies using light transmission aggregometry (LTA) have...

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Veröffentlicht in:	Journal of the American College of Cardiology 2009-03, Vol.53 (10), p.849-856
Hauptverfasser:	Sibbing, Dirk, MD, Braun, Siegmund, MD, Morath, Tanja, MS, Mehilli, Julinda, MD, Vogt, Wolfgang, MD, Schömig, Albert, MD, Kastrati, Adnan, MD, von Beckerath, Nicolas, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute coronary syndromes Aged Anticoagulants Aspirin Biological and medical sciences Blood platelets Cardiology Cardiology. Vascular system Cardiovascular Cardiovascular disease clopidogrel Confidence intervals Coronary Artery Disease - mortality Coronary Artery Disease - therapy Coronary vessels Drug dosages Drug therapy Drug-Eluting Stents - adverse effects Electric Impedance Electrodes Female Heart attacks Humans Internal Medicine Intervention Kaplan-Meier Estimate Male Medical imaging Medical sciences platelet aggregation Platelet Aggregation - drug effects Platelet Aggregation Inhibitors - adverse effects Platelet Aggregation Inhibitors - pharmacology Platelet Aggregation Inhibitors - therapeutic use Platelet Function Tests - instrumentation Platelet Function Tests - methods Point-of-Care Systems Prospective Studies stent thrombosis Stents Studies Thrombosis Thrombosis - epidemiology Thrombosis - etiology Ticlopidine - adverse effects Ticlopidine - analogs & derivatives Ticlopidine - pharmacology Ticlopidine - therapeutic use whole blood aggregometry
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