Omeprazole: A Possible New Candidate Influencing the Antiplatelet Effect of ClopidogrelEditorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology

[...]because the primary premise of this study is that the omeprazole-clopidogrel drug-drug interaction is via a CYP2C19 competitive or noncompetitive inhibitory mechanism, all known patients with CYP2C19 polymorphism should be excluded. Because heterozygous CYP2C19*2(*1/*2) genetic polymorphism lea...

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Veröffentlicht in:	Journal of the American College of Cardiology 2008-01, Vol.51 (3), p.261
Hauptverfasser:	Gurbel, Paul A, Lau, Wei C, Tantry, Udaya S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute coronary syndromes Blood platelets Cardiology Cardiovascular disease Drug dosages Drug therapy Medical research Metabolites Patients Phosphorylation Studies
Online-Zugang:	Volltext
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