Beraprost therapy for pulmonary arterial hypertension

The purpose of this study was to assess the safety and efficacy of the oral prostacyclin analogue beraprost sodium during a 12-month double-blind, randomized, placebo-controlled trial in patients with pulmonary arterial hypertension (PAH). Pulmonary arterial hypertension is a progressive disease tha...

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Veröffentlicht in:	Journal of the American College of Cardiology 2003-06, Vol.41 (12), p.2119-2125
Hauptverfasser:	Barst, Robyn J, McGoon, Michael, McLaughlin, Vallerie, Tapson, Victor, Oudiz, Ronald, Shapiro, Shelley, Robbins, Ivan M, Channick, Richard, Badesch, David, Rayburn, Barry K, Flinchbaugh, Robin, Sigman, Jeff, Arneson, Carl, Jeffs, Roger
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Cardiology Disease Dose-Response Relationship, Drug Double-Blind Method Drug Administration Schedule Drug therapy Epoprostenol - administration & dosage Epoprostenol - adverse effects Epoprostenol - analogs & derivatives Epoprostenol - therapeutic use Exercise Tolerance - drug effects Exercise Tolerance - physiology Female Follow-Up Studies Heart Heart rate Hemodynamics - drug effects Hemodynamics - physiology Humans Hypertension Hypertension, Pulmonary - drug therapy Hypertension, Pulmonary - physiopathology Male Pain Patients Pulmonary arteries Quality of Life Severity of Illness Index Tablets Time Factors Vasodilator Agents - administration & dosage Vasodilator Agents - adverse effects Vasodilator Agents - therapeutic use Ventilation
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