Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells

Abstract There is increasing evidence that certain natural compounds found in plants may be useful as cancer chemopreventive or chemotherapeutic agents. Limited in vitro studies indicate that several prenylated flavonoids present in the hop plant ( Humulus lupulus ) possess anticarcinogenic properti...

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Veröffentlicht in:	Cancer letters 2007-02, Vol.246 (1), p.201-209
Hauptverfasser:	Colgate, Emily C, Miranda, Cristobal L, Stevens, Jan F, Bray, Tammy M, Ho, Emily
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Apoptosis - drug effects Biotechnology Blotting, Western Carcinogens Cell Cycle - drug effects Cell growth Cell Line, Tumor Cell Survival - drug effects Data analysis Diet and cancer Dietary supplements Dilution Dose-Response Relationship, Drug Enzymes Epithelial Cells - drug effects Epithelial Cells - metabolism Epithelial Cells - pathology Flavonoids - chemistry Flavonoids - pharmacology Flow Cytometry Free radicals Hematology, Oncology and Palliative Medicine Humans Humulus - chemistry Male Molecular Structure Mortality NF-kappa B - antagonists & inhibitors NF-kappa B - metabolism NF-kappaB Propiophenones - chemistry Propiophenones - pharmacology Prostate cancer Prostatic Hyperplasia - metabolism Prostatic Hyperplasia - pathology Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Software Studies Xanthohumol
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