Plasmacytoid Dendritic Cell Recruitment to Murine Lung During Paramyxoviral Infection is Type I Ifn Receptor Dependent

Plasmacytoid Dendritic Cell Recruitment to Murine Lung During Paramyxoviral Infection is Type I Ifn Receptor Dependent

Plasmacytoid dendritic cells (pDC), which are identified by either the pDC specific antibody, PDCA-1, or high B220 and low level CD11c expression, are the major IFNalpha producing cells in the innate immune response and are thought to play a primary role in anti-viral defenses.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of allergy and clinical immunology 2006-02, Vol.117 (2), p.S241-S241
Hauptverfasser: Joo, S.S., Rohlfing, M.M., Grayson, M.H.
Format: Artikel
Sprache:eng
Schlagworte:
Immune system
Lymphatic system
Spleen
Viral infections
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Zusammenfassung:Plasmacytoid dendritic cells (pDC), which are identified by either the pDC specific antibody, PDCA-1, or high B220 and low level CD11c expression, are the major IFNalpha producing cells in the innate immune response and are thought to play a primary role in anti-viral defenses.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2005.12.955