Immune Regulation by CD4+CD25+ regulatory T cells in Patients with Japanese Cedar Pollinosis

The production of IFN-Î³, but not that of IL-5 was significantly enhanced in CD4+CD25- cell cultures compared to that in CD4+ cell cultures. [...]in specimens from patients showing enhanced immune responses, the addition of anti-GITR to cocultures of PBMC with allergen increased the production of Th...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2010-02, Vol.125 (2), p.AB144-AB144
Hauptverfasser:	Yamanishi, T, Chikamatsu, K, Takahashi, G, Endo, S, Masuyama, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Lymphocytes Medical research
Online-Zugang:	Volltext
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Zusammenfassung:	The production of IFN-Î³, but not that of IL-5 was significantly enhanced in CD4+CD25- cell cultures compared to that in CD4+ cell cultures. [...]in specimens from patients showing enhanced immune responses, the addition of anti-GITR to cocultures of PBMC with allergen increased the production of Th1 or Th2 cytokine.
ISSN:	0091-6749 1097-6825
DOI:	10.1016/j.jaci.2009.12.566