Mast cells in the innate immune response of the middle ear
New pathophysiologic concepts are needed to explain the clinically observed connection between the allergic diathesis and otitis media (OM). Since mast cells are the only leucocytes present in substantial numbers in the normal middle ear mucosa and are known to participate in innate immunity, we exa...
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Veröffentlicht in: | Journal of allergy and clinical immunology 2005-02, Vol.115 (2), p.S187-S187 |
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container_title | Journal of allergy and clinical immunology |
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creator | Ebmeyer, J. Furukawa, M. Pak, K.K. Ebmeyer, U. Sudhoff, H.H. Broide, D.H. Ryan, A.F. Wasserman, S.I. |
description | New pathophysiologic concepts are needed to explain the clinically observed connection between the allergic diathesis and otitis media (OM). Since mast cells are the only leucocytes present in substantial numbers in the normal middle ear mucosa and are known to participate in innate immunity, we examined their contributions to the pathogenesis of OM. |
doi_str_mv | 10.1016/j.jaci.2004.12.761 |
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subjects | Cytokines Ear diseases Immune system Pathogenesis Rodents |
title | Mast cells in the innate immune response of the middle ear |
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