Benzocaine anaphylaxis
In a 10-year retrospective study of 5464 patients subjected to patch testing with mixes of numerous caine drugs, benzocaine accounted for 22 out of 91 patients whose reactions were deemed allergic, and therefore 22 of 5464 (0.4%) patients had positive type IV reactions to benzocaine.5 No patients re...
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Veröffentlicht in: | Journal of allergy and clinical immunology 2006-08, Vol.118 (2), p.534-535 |
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description | In a 10-year retrospective study of 5464 patients subjected to patch testing with mixes of numerous caine drugs, benzocaine accounted for 22 out of 91 patients whose reactions were deemed allergic, and therefore 22 of 5464 (0.4%) patients had positive type IV reactions to benzocaine.5 No patients reported symptoms consistent with immediate hypersensitivity (type I). Positive skin test reactions to amide anesthetics (articaine, lidocaine) have been reported in 2 cases, but these patients received the injectable form and only had mild reactions (cutaneous without loss of consciousness).7,8 There have also been reports of anaphylaxis to lidocaine9 and lignocaine,10 but these agents were given intravenously. |
doi_str_mv | 10.1016/j.jaci.2006.04.035 |
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Positive skin test reactions to amide anesthetics (articaine, lidocaine) have been reported in 2 cases, but these patients received the injectable form and only had mild reactions (cutaneous without loss of consciousness).7,8 There have also been reports of anaphylaxis to lidocaine9 and lignocaine,10 but these agents were given intravenously.</description><identifier>ISSN: 0091-6749</identifier><identifier>EISSN: 1097-6825</identifier><identifier>DOI: 10.1016/j.jaci.2006.04.035</identifier><identifier>PMID: 16890789</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Allergies ; Anaphylaxis - etiology ; Anaphylaxis - immunology ; Anesthetics, Local - adverse effects ; Anesthetics, Local - immunology ; Benzocaine - adverse effects ; Benzocaine - immunology ; Consciousness ; Dilution ; Female ; Humans ; Intradermal Tests ; Middle Aged ; Patients</subject><ispartof>Journal of allergy and clinical immunology, 2006-08, Vol.118 (2), p.534-535</ispartof><rights>2006 American Academy of Allergy, Asthma and Immunology</rights><rights>Copyright Elsevier Limited Aug 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c351t-231c2babd74aa8387e7581ed525b1b389e0b4b0752954687c475509679f00313</citedby><cites>FETCH-LOGICAL-c351t-231c2babd74aa8387e7581ed525b1b389e0b4b0752954687c475509679f00313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jaci.2006.04.035$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16890789$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vu, Alexander Trien</creatorcontrib><creatorcontrib>Lockey, Richard Funk</creatorcontrib><title>Benzocaine anaphylaxis</title><title>Journal of allergy and clinical immunology</title><addtitle>J Allergy Clin Immunol</addtitle><description>In a 10-year retrospective study of 5464 patients subjected to patch testing with mixes of numerous caine drugs, benzocaine accounted for 22 out of 91 patients whose reactions were deemed allergic, and therefore 22 of 5464 (0.4%) patients had positive type IV reactions to benzocaine.5 No patients reported symptoms consistent with immediate hypersensitivity (type I). Positive skin test reactions to amide anesthetics (articaine, lidocaine) have been reported in 2 cases, but these patients received the injectable form and only had mild reactions (cutaneous without loss of consciousness).7,8 There have also been reports of anaphylaxis to lidocaine9 and lignocaine,10 but these agents were given intravenously.</description><subject>Allergies</subject><subject>Anaphylaxis - etiology</subject><subject>Anaphylaxis - immunology</subject><subject>Anesthetics, Local - adverse effects</subject><subject>Anesthetics, Local - immunology</subject><subject>Benzocaine - adverse effects</subject><subject>Benzocaine - immunology</subject><subject>Consciousness</subject><subject>Dilution</subject><subject>Female</subject><subject>Humans</subject><subject>Intradermal Tests</subject><subject>Middle Aged</subject><subject>Patients</subject><issn>0091-6749</issn><issn>1097-6825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1LAzEUxIMotlavHjyI4HnXl-8EvGjxCwpeeg9JNsUs7W5NtmL9601pwZunx4PfzDCD0BWGGgMWd23dWh9rAiBqYDVQfoTGGLSshCL8GI0BNK6EZHqEznJuofxU6VM0wkJpkEqP0eVj6H56b2MXbmxn1x_bpf2O-RydLOwyh4vDnaD589N8-lrN3l_epg-zylOOh4pQ7ImzrpHMWkWVDJIrHBpOuMOuZAVwzIHkRHMmlPRMcg5aSL0AoJhO0O3edp36z03Ig2n7TepKosEcCoylVIUie8qnPucUFmad4sqmrcFgdkuY1uyWMLslDDBTliii64P1xq1C8yc5VC_A_R4Ipd9XDMlkH0PnQxNT8INp-vif_y84pmuo</recordid><startdate>20060801</startdate><enddate>20060801</enddate><creator>Vu, Alexander Trien</creator><creator>Lockey, Richard Funk</creator><general>Mosby, Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>20060801</creationdate><title>Benzocaine anaphylaxis</title><author>Vu, Alexander Trien ; Lockey, Richard Funk</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c351t-231c2babd74aa8387e7581ed525b1b389e0b4b0752954687c475509679f00313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Allergies</topic><topic>Anaphylaxis - etiology</topic><topic>Anaphylaxis - immunology</topic><topic>Anesthetics, Local - adverse effects</topic><topic>Anesthetics, Local - immunology</topic><topic>Benzocaine - adverse effects</topic><topic>Benzocaine - immunology</topic><topic>Consciousness</topic><topic>Dilution</topic><topic>Female</topic><topic>Humans</topic><topic>Intradermal Tests</topic><topic>Middle Aged</topic><topic>Patients</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vu, Alexander Trien</creatorcontrib><creatorcontrib>Lockey, Richard Funk</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Journal of allergy and clinical immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vu, Alexander Trien</au><au>Lockey, Richard Funk</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Benzocaine anaphylaxis</atitle><jtitle>Journal of allergy and clinical immunology</jtitle><addtitle>J Allergy Clin Immunol</addtitle><date>2006-08-01</date><risdate>2006</risdate><volume>118</volume><issue>2</issue><spage>534</spage><epage>535</epage><pages>534-535</pages><issn>0091-6749</issn><eissn>1097-6825</eissn><abstract>In a 10-year retrospective study of 5464 patients subjected to patch testing with mixes of numerous caine drugs, benzocaine accounted for 22 out of 91 patients whose reactions were deemed allergic, and therefore 22 of 5464 (0.4%) patients had positive type IV reactions to benzocaine.5 No patients reported symptoms consistent with immediate hypersensitivity (type I). Positive skin test reactions to amide anesthetics (articaine, lidocaine) have been reported in 2 cases, but these patients received the injectable form and only had mild reactions (cutaneous without loss of consciousness).7,8 There have also been reports of anaphylaxis to lidocaine9 and lignocaine,10 but these agents were given intravenously.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>16890789</pmid><doi>10.1016/j.jaci.2006.04.035</doi><tpages>2</tpages></addata></record> |
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subjects | Allergies Anaphylaxis - etiology Anaphylaxis - immunology Anesthetics, Local - adverse effects Anesthetics, Local - immunology Benzocaine - adverse effects Benzocaine - immunology Consciousness Dilution Female Humans Intradermal Tests Middle Aged Patients |
title | Benzocaine anaphylaxis |
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