Thyrotoxic hypercoagulable state with cerebral venous thrombosis and venous infarction masquerading as epilepsia partialis continua
Physical examination showed sinus tachycardia (heart rate-115 beats/min), warm clammy skin, left upper extremity weakness of a pyramidal pattern and left-sided facial sensory impairment to touch and pin prick over the V1 and V2 distribution. Contrast-enhanced brain magnetic resonance imaging reveale...
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Veröffentlicht in: | Neurology India 2013-11, Vol.61 (6), p.671 |
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description | Physical examination showed sinus tachycardia (heart rate-115 beats/min), warm clammy skin, left upper extremity weakness of a pyramidal pattern and left-sided facial sensory impairment to touch and pin prick over the V1 and V2 distribution. Contrast-enhanced brain magnetic resonance imaging revealed a filling defect in the superior sagittal sinus and a small right frontal hemorrhagic infarct [Figure 2]a and b. Magnetic resonance venography (MRV) of the brain revealed extensive sub-acute superior sagittal and transverse sinus thrombosis [Figure 2]c and d. Endocrinological work-up revealed severe thyrotoxicosis (undetectable thyroid stimulating hormone |
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Contrast-enhanced brain magnetic resonance imaging revealed a filling defect in the superior sagittal sinus and a small right frontal hemorrhagic infarct [Figure 2]a and b. Magnetic resonance venography (MRV) of the brain revealed extensive sub-acute superior sagittal and transverse sinus thrombosis [Figure 2]c and d. Endocrinological work-up revealed severe thyrotoxicosis (undetectable thyroid stimulating hormone <0.005 mIU/L, high T3 at 209 ng/dL [N = 58-159 ng/dL], high free T3 at 17.6 pg/mL [N = 2-4.4 pg/mL] and high free T4 at 18.6 [mu]g/dL [N = 4.5-12.0 [mu]g/dL]).</description><identifier>ISSN: 0028-3886</identifier><identifier>EISSN: 1998-4022</identifier><identifier>DOI: 10.4103/0028-3886.125370</identifier><identifier>PMID: 24441348</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Blood clot ; Case studies ; Cerebral Infarction - complications ; Cerebral Infarction - physiopathology ; Diagnosis ; Drug therapy ; Epilepsia Partialis Continua - etiology ; Female ; Health aspects ; Humans ; Hyperthyroidism ; Intracranial Thrombosis - complications ; Intracranial Thrombosis - physiopathology ; Magnetic resonance imaging ; Middle Aged ; Proteins ; Sinuses ; Thrombosis ; Thyrotoxicosis - complications ; Thyrotoxicosis - physiopathology ; Venous Thrombosis - complications ; Venous Thrombosis - physiopathology ; Warfarin</subject><ispartof>Neurology India, 2013-11, Vol.61 (6), p.671</ispartof><rights>COPYRIGHT 2013 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications & Media Pvt Ltd Nov-Dec 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c399t-94066e2368ed2563f468d4ab7979be292e9a6e6fb9df8c9f6584ff686fa9e1873</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24441348$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chhabra, Lovely</creatorcontrib><creatorcontrib>Chaubey, Vinod K</creatorcontrib><creatorcontrib>Joshi, Saurabh</creatorcontrib><creatorcontrib>Phadke, Jayant</creatorcontrib><title>Thyrotoxic hypercoagulable state with cerebral venous thrombosis and venous infarction masquerading as epilepsia partialis continua</title><title>Neurology India</title><addtitle>Neurol India</addtitle><description>Physical examination showed sinus tachycardia (heart rate-115 beats/min), warm clammy skin, left upper extremity weakness of a pyramidal pattern and left-sided facial sensory impairment to touch and pin prick over the V1 and V2 distribution. Contrast-enhanced brain magnetic resonance imaging revealed a filling defect in the superior sagittal sinus and a small right frontal hemorrhagic infarct [Figure 2]a and b. Magnetic resonance venography (MRV) of the brain revealed extensive sub-acute superior sagittal and transverse sinus thrombosis [Figure 2]c and d. Endocrinological work-up revealed severe thyrotoxicosis (undetectable thyroid stimulating hormone <0.005 mIU/L, high T3 at 209 ng/dL [N = 58-159 ng/dL], high free T3 at 17.6 pg/mL [N = 2-4.4 pg/mL] and high free T4 at 18.6 [mu]g/dL [N = 4.5-12.0 [mu]g/dL]).</description><subject>Blood clot</subject><subject>Case studies</subject><subject>Cerebral Infarction - complications</subject><subject>Cerebral Infarction - physiopathology</subject><subject>Diagnosis</subject><subject>Drug therapy</subject><subject>Epilepsia Partialis Continua - etiology</subject><subject>Female</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Hyperthyroidism</subject><subject>Intracranial Thrombosis - complications</subject><subject>Intracranial Thrombosis - physiopathology</subject><subject>Magnetic resonance imaging</subject><subject>Middle Aged</subject><subject>Proteins</subject><subject>Sinuses</subject><subject>Thrombosis</subject><subject>Thyrotoxicosis - complications</subject><subject>Thyrotoxicosis - physiopathology</subject><subject>Venous Thrombosis - complications</subject><subject>Venous Thrombosis - physiopathology</subject><subject>Warfarin</subject><issn>0028-3886</issn><issn>1998-4022</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkc2L3CAchqW0dGe3vfdUhJ4zNWqMHpelX7DQy_YsxvyccUk0VdN2zv3H6zD7QWHwIOrzqC8vQu9asuUtYR8JobJhUoptSzvWkxdo0yolG04ofYk2T8cX6DLn-7pkrKWv0QXlnLeMyw36e7c_pFjiH2_x_rBAstHs1skME-BcTAH825c9tpBgSGbCvyDENeOyT3EeYvYZmzA-7vrgTLLFx4Bnk3-ukMzoww6bjGHxEyzZG7yYVLyZqmljKD6s5g165cyU4e3DfIV-fP50d_O1uf3-5dvN9W1jmVKlUZwIAZQJCSPtBHNcyJGboVe9GoAqCsoIEG5Qo5NWOdFJ7pyQwhkFrezZFfpwundJsX4uF30f1xTqk7rtCO256EX3TO3MBLpGiiUZO_ts9TXrJGVUdaxSzRlqB6FmnmIAV-P-z2_P8HWMMHt7ViAnwaaYcwKnl-Rnkw66JfpYvj62q4_t6lP5VXn_kG8dZhifhMe22T_D-Ks3</recordid><startdate>20131101</startdate><enddate>20131101</enddate><creator>Chhabra, Lovely</creator><creator>Chaubey, Vinod K</creator><creator>Joshi, Saurabh</creator><creator>Phadke, Jayant</creator><general>Medknow Publications and Media Pvt. 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subjects | Blood clot Case studies Cerebral Infarction - complications Cerebral Infarction - physiopathology Diagnosis Drug therapy Epilepsia Partialis Continua - etiology Female Health aspects Humans Hyperthyroidism Intracranial Thrombosis - complications Intracranial Thrombosis - physiopathology Magnetic resonance imaging Middle Aged Proteins Sinuses Thrombosis Thyrotoxicosis - complications Thyrotoxicosis - physiopathology Venous Thrombosis - complications Venous Thrombosis - physiopathology Warfarin |
title | Thyrotoxic hypercoagulable state with cerebral venous thrombosis and venous infarction masquerading as epilepsia partialis continua |
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