WNT7B mediates autocrine Wnt/[beta]-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma

Developmental and cancer models show Wnt/[beta]-catenin-dependent signaling mediates diverse phenotypic outcomes in the pancreas that are dictated by context, duration and strength of activation. While generally assumed to be pro-tumorigenic, it is unclear to what extent dysregulation of Wnt/[beta]-...

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Veröffentlicht in:	Oncogene 2014-02, Vol.33 (7), p.899
Hauptverfasser:	Arensman, M D, Kovochich, A N, Kulikauskas, R M, Lay, A R, Yang, P-t, Li, X, Donahue, T, Major, M B, Moon, R T, Chien, A J, Dawson, D W
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene expression Genotype & phenotype Pancreatic cancer Signal transduction
Online-Zugang:	Volltext
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