Hot melt mixing and foaming of soluplus® and indomethacin

The hot melt mixing (HMM) process was used to dissolve 30 wt% of a model drug, indomethacin (INM), in Soluplus® a water soluble polymer excipient. Comprehensive characterization of the HMM‐prepared samples, using differential scanning calorimetry, X‐ray diffraction, Fourier Transform Infrared spectr...

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Veröffentlicht in:	Polymer engineering and science 2012-08, Vol.52 (8), p.1629-1639
Hauptverfasser:	Terife, Graciela, Wang, Peng, Faridi, Niloufar, Gogos, Costas G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidity Applied sciences Aqueous solutions Carbon dioxide Chemical processes Chemical properties Composition Dissolution Exact sciences and technology Hydrogen bonds Identification and classification Indomethacin Methods Mixing Physicochemistry of polymers Polymer industry, paints, wood Polymer melt processing Production processes Spectrum analysis Technology of polymers
Online-Zugang:	Volltext
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