Critical role of nitric oxide in the modulation of prepulse inhibition in Swiss mice

Rationale Nitric oxide (NO) modulates the dopamine uptake and release processes and appears to be implicated in dopamine-related pathologies, such as schizophrenia. However, it is unclear whether there is excess or deficient NO synthesis in schizophrenia pathophysiology. Analyses of the intracellula...

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Veröffentlicht in:	Psychopharmacology 2014-02, Vol.231 (4), p.663-672
Hauptverfasser:	Issy, Ana C., Pedrazzi, João Francisco C., Yoneyama, Bruno H., Del-Bel, Elaine A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Amphetamine - pharmacology Analysis Animal behavior Animals Biomedical and Life Sciences Biomedicine Cyclic AMP - metabolism Cyclic GMP - metabolism Dopamine Dopamine Agents - pharmacology Dose-Response Relationship, Drug Guanylate Cyclase - antagonists & inhibitors Guanylate Cyclase - metabolism Inhibition (Psychology) Male Mice Neuropsychological Tests Neurosciences Nitric oxide Nitric Oxide - metabolism Nitric Oxide Donors - pharmacology Nitroprusside - pharmacology Original Investigation Perceptual-motor processes Pharmacology/Toxicology Phosphodiesterase Inhibitors - pharmacology Phosphoric Diester Hydrolases - metabolism Physiological aspects Psychiatry Psychopharmacology Purinones - pharmacology Reflex, Startle - drug effects Reflex, Startle - physiology Rodents Schizophrenia Sensory Gating - drug effects Sensory Gating - physiology
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