Direct detection of neuropeptide dynorphin A binding to the second extracellular loop of the [kappa] opioid receptor using a soluble protein scaffold

The molecular determinants for selectivity of ligand binding to membrane receptors are of key importance for the understanding of cellular signalling, as well as for rational therapeutic intervention. In the present study, we target the interaction between the [kappa] opioid receptor (KOR) and its n...

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Veröffentlicht in:	The FEBS journal 2014-02, Vol.281 (3), p.814
Hauptverfasser:	Bjorneras, Johannes, Kurnik, Martin, Oliveberg, Mikael, Graslund, Astrid, Maler, Lena, Danielsson, Jens
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular biology Ligands Molecular biology Peptides Proteins
Online-Zugang:	Volltext
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