A users' guide to understanding therapeutic substitutions

Abstract Therapeutic substitutions are common at the level of ministries of health, clinicians, and pharmacy dispensaries. Guidance in determining whether drugs offer similar risk–benefit profiles is limited. Those making decisions on therapeutic substitutions should be aware of potential biases tha...

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Veröffentlicht in:	Journal of clinical epidemiology 2014-03, Vol.67 (3), p.305-313
Hauptverfasser:	Mills, Edward J, Gardner, David, Thorlund, Kristian, Briel, Matthias, Bryan, Stirling, Hutton, Brian, Guyatt, Gordon H
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis. Health state Bias Biological and medical sciences Blood pressure Class effects Confidence intervals Decision Making Drug formularies Drug stores Drug Substitution - methods Drug Substitution - standards Drug therapy Epidemiology Evidence-Based Medicine Female General aspects Generic substitutions Hospitals Humans Internal Medicine Male Medical research Medical sciences Methodology Mortality Network meta-analysis Patients Prescription Drugs - administration & dosage Prescription Drugs - standards Product safety Public health. Hygiene Public health. Hygiene-occupational medicine Randomized Controlled Trials as Topic Risk Assessment Statins Therapeutic Equivalency Therapeutic substitutions
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