Fatal acute pancreatitis in a patient with visceral leishmaniasis during miltefosine treatment
Pancreatitis is a known side effect of the once commonly used drug, sodium stibogluconate, for treatment of visceral leishmaniasis (VL). In India, miltefosine has recently been introduced as the first-line drug. Its side effects include loose motions, vomiting, and teratogenicity. We report here a c...
Gespeichert in:
| Veröffentlicht in: | Journal of postgraduate medicine 2013-10, Vol.59 (4), p.306-308 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 308 |
|---|---|
| container_issue | 4 |
| container_start_page | 306 |
| container_title | Journal of postgraduate medicine |
| container_volume | 59 |
| creator | Pandey, K Singh, D Lal, C S Das, V N R Das, P |
| description | Pancreatitis is a known side effect of the once commonly used drug, sodium stibogluconate, for treatment of visceral leishmaniasis (VL). In India, miltefosine has recently been introduced as the first-line drug. Its side effects include loose motions, vomiting, and teratogenicity. We report here a case of a 41-year-old parasitologically confirmed male case of VL, who developed acute pancreatitis during treatment with miltefosine. On the 13 th day of treatment, he presented with abdominal pain and vomiting. The biochemical, hematological, and radiological features were suggestive of acute pancreatitis. The patient was put on conservative treatment for pancreatitis at the specialized center but succumbed to renal failure and septicaemia. |
| doi_str_mv | 10.4103/0022-3859.123161 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_journals_1476384569</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A354989419</galeid><sourcerecordid>A354989419</sourcerecordid><originalsourceid>FETCH-LOGICAL-c474t-72c440e468f06d1ef628323e0769b4005b23e9830808271a36d512f539e08c8a3</originalsourceid><addsrcrecordid>eNptkctr3DAQxkVpaV6991QMPXszeliWjiEkbSCQS3qN0MrjjYItbyU5If99ZDYPAosO0ox-3wwfHyE_KawEBX4KwFjNVaNXlHEq6RdyCLplNVOMfy3vt-8DcpTSAwCVUvDv5IAJLiRX-pDcXdpsh8q6OWO1tcFFtNlnnyofKls62WPI1ZPP99WjTw5joQf06X60wdtUwG6OPmyq0Q8Z-yn5gFVepoxFeEK-9XZI-OP1Pib_Li9uz__W1zd_rs7PrmsnWpHrljkhAIVUPciOYi-Z4owjtFKvBUCzLoVWHBQo1lLLZddQ1jdcIyinLD8mv3dzt3H6P2PK5mGaYygrDRVtsSoaqT-ojR3Q-NBPOVo3FlvmjDdCKy3oQtV7qA2GxfsUsPel_Ylf7eHL6XD0bq8AdgIXp5Qi9mYb_Wjjs6FgllzNEpxZgjO7XIvk16u_eT1i9y54C5K_AC6Lmq8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1476384569</pqid></control><display><type>article</type><title>Fatal acute pancreatitis in a patient with visceral leishmaniasis during miltefosine treatment</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Pandey, K ; Singh, D ; Lal, C S ; Das, V N R ; Das, P</creator><creatorcontrib>Pandey, K ; Singh, D ; Lal, C S ; Das, V N R ; Das, P</creatorcontrib><description>Pancreatitis is a known side effect of the once commonly used drug, sodium stibogluconate, for treatment of visceral leishmaniasis (VL). In India, miltefosine has recently been introduced as the first-line drug. Its side effects include loose motions, vomiting, and teratogenicity. We report here a case of a 41-year-old parasitologically confirmed male case of VL, who developed acute pancreatitis during treatment with miltefosine. On the 13 th day of treatment, he presented with abdominal pain and vomiting. The biochemical, hematological, and radiological features were suggestive of acute pancreatitis. The patient was put on conservative treatment for pancreatitis at the specialized center but succumbed to renal failure and septicaemia.</description><identifier>ISSN: 0022-3859</identifier><identifier>EISSN: 0972-2823</identifier><identifier>DOI: 10.4103/0022-3859.123161</identifier><identifier>PMID: 24346389</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Adult ; Antiprotozoal Agents - adverse effects ; Care and treatment ; Drug therapy ; Fatal Outcome ; Humans ; Kala-azar ; Leishmaniasis, Visceral - drug therapy ; Male ; Pancreatitis ; Pancreatitis, Acute Necrotizing - chemically induced ; Pancreatitis, Acute Necrotizing - diagnostic imaging ; Phosphorylcholine - adverse effects ; Phosphorylcholine - analogs & derivatives ; Radiography</subject><ispartof>Journal of postgraduate medicine, 2013-10, Vol.59 (4), p.306-308</ispartof><rights>COPYRIGHT 2013 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications & Media Pvt Ltd Oct 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-72c440e468f06d1ef628323e0769b4005b23e9830808271a36d512f539e08c8a3</citedby><cites>FETCH-LOGICAL-c474t-72c440e468f06d1ef628323e0769b4005b23e9830808271a36d512f539e08c8a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24346389$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pandey, K</creatorcontrib><creatorcontrib>Singh, D</creatorcontrib><creatorcontrib>Lal, C S</creatorcontrib><creatorcontrib>Das, V N R</creatorcontrib><creatorcontrib>Das, P</creatorcontrib><title>Fatal acute pancreatitis in a patient with visceral leishmaniasis during miltefosine treatment</title><title>Journal of postgraduate medicine</title><addtitle>J Postgrad Med</addtitle><description>Pancreatitis is a known side effect of the once commonly used drug, sodium stibogluconate, for treatment of visceral leishmaniasis (VL). In India, miltefosine has recently been introduced as the first-line drug. Its side effects include loose motions, vomiting, and teratogenicity. We report here a case of a 41-year-old parasitologically confirmed male case of VL, who developed acute pancreatitis during treatment with miltefosine. On the 13 th day of treatment, he presented with abdominal pain and vomiting. The biochemical, hematological, and radiological features were suggestive of acute pancreatitis. The patient was put on conservative treatment for pancreatitis at the specialized center but succumbed to renal failure and septicaemia.</description><subject>Adult</subject><subject>Antiprotozoal Agents - adverse effects</subject><subject>Care and treatment</subject><subject>Drug therapy</subject><subject>Fatal Outcome</subject><subject>Humans</subject><subject>Kala-azar</subject><subject>Leishmaniasis, Visceral - drug therapy</subject><subject>Male</subject><subject>Pancreatitis</subject><subject>Pancreatitis, Acute Necrotizing - chemically induced</subject><subject>Pancreatitis, Acute Necrotizing - diagnostic imaging</subject><subject>Phosphorylcholine - adverse effects</subject><subject>Phosphorylcholine - analogs & derivatives</subject><subject>Radiography</subject><issn>0022-3859</issn><issn>0972-2823</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkctr3DAQxkVpaV6991QMPXszeliWjiEkbSCQS3qN0MrjjYItbyU5If99ZDYPAosO0ox-3wwfHyE_KawEBX4KwFjNVaNXlHEq6RdyCLplNVOMfy3vt-8DcpTSAwCVUvDv5IAJLiRX-pDcXdpsh8q6OWO1tcFFtNlnnyofKls62WPI1ZPP99WjTw5joQf06X60wdtUwG6OPmyq0Q8Z-yn5gFVepoxFeEK-9XZI-OP1Pib_Li9uz__W1zd_rs7PrmsnWpHrljkhAIVUPciOYi-Z4owjtFKvBUCzLoVWHBQo1lLLZddQ1jdcIyinLD8mv3dzt3H6P2PK5mGaYygrDRVtsSoaqT-ojR3Q-NBPOVo3FlvmjDdCKy3oQtV7qA2GxfsUsPel_Ylf7eHL6XD0bq8AdgIXp5Qi9mYb_Wjjs6FgllzNEpxZgjO7XIvk16u_eT1i9y54C5K_AC6Lmq8</recordid><startdate>20131001</startdate><enddate>20131001</enddate><creator>Pandey, K</creator><creator>Singh, D</creator><creator>Lal, C S</creator><creator>Das, V N R</creator><creator>Das, P</creator><general>Medknow Publications and Media Pvt. Ltd</general><general>Medknow Publications & Media Pvt. Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope></search><sort><creationdate>20131001</creationdate><title>Fatal acute pancreatitis in a patient with visceral leishmaniasis during miltefosine treatment</title><author>Pandey, K ; Singh, D ; Lal, C S ; Das, V N R ; Das, P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-72c440e468f06d1ef628323e0769b4005b23e9830808271a36d512f539e08c8a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Antiprotozoal Agents - adverse effects</topic><topic>Care and treatment</topic><topic>Drug therapy</topic><topic>Fatal Outcome</topic><topic>Humans</topic><topic>Kala-azar</topic><topic>Leishmaniasis, Visceral - drug therapy</topic><topic>Male</topic><topic>Pancreatitis</topic><topic>Pancreatitis, Acute Necrotizing - chemically induced</topic><topic>Pancreatitis, Acute Necrotizing - diagnostic imaging</topic><topic>Phosphorylcholine - adverse effects</topic><topic>Phosphorylcholine - analogs & derivatives</topic><topic>Radiography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pandey, K</creatorcontrib><creatorcontrib>Singh, D</creatorcontrib><creatorcontrib>Lal, C S</creatorcontrib><creatorcontrib>Das, V N R</creatorcontrib><creatorcontrib>Das, P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><jtitle>Journal of postgraduate medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pandey, K</au><au>Singh, D</au><au>Lal, C S</au><au>Das, V N R</au><au>Das, P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fatal acute pancreatitis in a patient with visceral leishmaniasis during miltefosine treatment</atitle><jtitle>Journal of postgraduate medicine</jtitle><addtitle>J Postgrad Med</addtitle><date>2013-10-01</date><risdate>2013</risdate><volume>59</volume><issue>4</issue><spage>306</spage><epage>308</epage><pages>306-308</pages><issn>0022-3859</issn><eissn>0972-2823</eissn><abstract>Pancreatitis is a known side effect of the once commonly used drug, sodium stibogluconate, for treatment of visceral leishmaniasis (VL). In India, miltefosine has recently been introduced as the first-line drug. Its side effects include loose motions, vomiting, and teratogenicity. We report here a case of a 41-year-old parasitologically confirmed male case of VL, who developed acute pancreatitis during treatment with miltefosine. On the 13 th day of treatment, he presented with abdominal pain and vomiting. The biochemical, hematological, and radiological features were suggestive of acute pancreatitis. The patient was put on conservative treatment for pancreatitis at the specialized center but succumbed to renal failure and septicaemia.</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>24346389</pmid><doi>10.4103/0022-3859.123161</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3859 |
| ispartof | Journal of postgraduate medicine, 2013-10, Vol.59 (4), p.306-308 |
| issn | 0022-3859 0972-2823 |
| language | eng |
| recordid | cdi_proquest_journals_1476384569 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Antiprotozoal Agents - adverse effects Care and treatment Drug therapy Fatal Outcome Humans Kala-azar Leishmaniasis, Visceral - drug therapy Male Pancreatitis Pancreatitis, Acute Necrotizing - chemically induced Pancreatitis, Acute Necrotizing - diagnostic imaging Phosphorylcholine - adverse effects Phosphorylcholine - analogs & derivatives Radiography |
| title | Fatal acute pancreatitis in a patient with visceral leishmaniasis during miltefosine treatment |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T02%3A13%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Fatal%20acute%20pancreatitis%20in%20a%20patient%20with%20visceral%20leishmaniasis%20during%20miltefosine%20treatment&rft.jtitle=Journal%20of%20postgraduate%20medicine&rft.au=Pandey,%20K&rft.date=2013-10-01&rft.volume=59&rft.issue=4&rft.spage=306&rft.epage=308&rft.pages=306-308&rft.issn=0022-3859&rft.eissn=0972-2823&rft_id=info:doi/10.4103/0022-3859.123161&rft_dat=%3Cgale_proqu%3EA354989419%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1476384569&rft_id=info:pmid/24346389&rft_galeid=A354989419&rfr_iscdi=true |