fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation

Human pluripotent stem cells (hPSCs), including human embryonic stem cells and induced pluripotent stem cells, are promising for numerous biomedical applications, such as cell replacement therapies, tissue and whole-organ engineering, and high-throughput pharmacology and toxicology screening. Each o...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2013-12, Vol.110 (52), p.E5039-E5048
Hauptverfasser:	Lei, Yuguo, Schaffer, David V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical research Cell Culture Techniques - methods Cell Differentiation - physiology Cell Proliferation embryonic stem cells engineering Humans hydrocolloids Hydrogels induced pluripotent stem cells Karyotyping Mice Neural Stem Cells - cytology Neurons pharmacology Physical Sciences Pluripotent Stem Cells - cytology Pluripotent Stem Cells - physiology PNAS Plus Proteins recombinant proteins screening Stem cells Teratoma - pathology Tissue Engineering - methods toxicology
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