[beta]2-Glycoprotein I binds to thrombin and selectively inhibits the enzyme procoagulant functions

Summary Background This work was aimed at characterizing the interaction of [beta]2-glycoprotein I ([beta]2GPI), an abundant plasma protein of unknown function, with human thrombin, the final effector protease in the coagulation cascade. Methods The [beta]2GPI-thrombin interaction was studied by sur...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2013-06, Vol.11 (6), p.1093
Hauptverfasser:	Pozzi, N, Acquasaliente, L, Frasson, R, Cristiani, A, Moro, S, Banzato, A, Pengo, V, Scaglione, G L, Arcovito, A, Cristofaro, R, Filippis, V
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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