A THREE-MONTH REPEATED ORAL ADMINISTRATION STUDY OF A LOW VISCOSITY GRADE OF HYDROXYPROPYL METHYLCELLULOSE IN RATS

The toxicity of the lowest viscosity grade of hydroxiprorpyl methylcellulose (HPMC) that is currently commercially available was investigated by means of a three-month repeated oral administration study in male and female Crj:CD (SD) IGS rats at doses of 505, 1, 020 and 2, 100 mg/kg/day. Body weight...

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Veröffentlicht in:	Journal of toxicological sciences 1999, Vol.24(1), pp.33-43
Hauptverfasser:	OBARA, Sakae, MUTO, Hiroaki, SHIGENO, Hitoshi, YOSHIDA, Ayako, NAGAYA, Jyun-ichi, HIRATA, Mariko, FURUKAWA, Masatoshi, SUNAGA, Masao
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Biological and medical sciences Blood Chemical Analysis Body Weight - drug effects Chemical and industrial products toxicology. Toxic occupational diseases Eating - drug effects Eye - drug effects Female Hypromellose Derivatives Male Medical sciences Methylcellulose - analogs & derivatives Methylcellulose - toxicity Organ Size - drug effects Rats Sex Factors Toxicity Toxicology Urine Various organic compounds Viscosity
Online-Zugang:	Volltext
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