FERTILITY STUDY OF TRANDOLAPRIL (RU44570) IN RATS

A fertility study was performed in Sprague-Dawley rats treated orally with trandolapril (RU44570) at the dosage levels of 3, 30 and 300 mg/kg/day. The male rats were treated for 63 days before mating and during the mating period. The female rats were treated from 14 days before mating to day 7 of pr...

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Veröffentlicht in:	Journal of toxicological sciences 1993/04/16, Vol.18(SupplementI), pp.93-105
Hauptverfasser:	MATSUURA, Tetsuro, KURIO, Wasako, FUJISHIMA, Hiroshi, KUMAGAI, Yasunori, NARAMA, Isao, HIRAMATSU, Yasuzo, TAKABATAKE, Eigo
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - toxicity Animals Female Fertility - drug effects Fetus - drug effects Indoles - toxicity Male Pregnancy rat Rats Rats, Sprague-Dawley
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