Green Tea Catechins Increase the Force of Contraction in Isolated Guinea Pig Atrial Muscle Preparations by Increasing the Amplitude of Intracellular Ca2+ Concentration

It has been reported that green tea catechins enhance the force of contraction of isolated heart muscle preparations. However, it remains controversial whether or not the increase in force of contraction is related to an increase in the intracellular Ca2+ concentration ([Ca2+]i). In this study, the...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2012, Vol.74(12), pp.1603-1608
Hauptverfasser:	SASAKI, Takushi, KAMATA, Ryo, UENO, Shunji, KANEDA, Takeharu, TEMMA, Kyosuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Camellia sinensis - chemistry Catechin - analogs & derivatives Catechin - chemistry Catechin - pharmacology Dose-Response Relationship, Drug epicatechin gallate epigallocatechin gallate force of contraction Guinea Pigs Heart Atria - drug effects intracellular Ca2+ concentration isolated guinea pig heart Male Molecular Structure Myocardial Contraction - drug effects Plant Extracts - pharmacology Regression Analysis
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