Histopathological effect of ketoconazole on rat placenta

In order to investigate the morphological effects of ketoconazole on hypertrophied placentas, we examined the sequential histopathological changes in the placenta from rats exposed to ketoconazole. Ketoconazole was administered orally at 0 and 25 mg/kg/day during gestation days (GDs) 12 to 14, and t...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2008, Vol.70(11), pp.1179-1184
Hauptverfasser:	Furukawa, S.(Nissan Chemical Industries Ltd., Shiraoka, Saitama (Japan). Biological Research Lab.), Hayashi, S, Usuda, K, Abe, M, Ogawa, I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Decidua - drug effects Decidua - pathology Female Fetal Death HIPERTROFIA HISTOPATHOLOGIE HISTOPATHOLOGY HISTOPATOLOGIA HYPERTROPHIE HYPERTROPHY IMIDAZOLE IMIDAZOLES ketoconazole Ketoconazole - adverse effects Mitosis - drug effects Organ Size - drug effects PLACENTA Placenta - anatomy & histology Placenta - drug effects Placenta - pathology Pregnancy RAT RATA RATS
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