Renal effects of medetomidine in isoflurane-anesthetized dogs with special reference to its diuretic action

Renal effects of the selective alpha2-adrenoceptor agonist, medetomidine, were investigated in anesthetized dogs. Animals were administered medetomidine 20 and 40 micro g/kg intravenously (IV) and 80 micro g/kg intramuscularly (IM) or 1 ml of saline IV. Urine and blood samples were collected before...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2005, Vol.67(5), pp.461-465
Hauptverfasser:	Saleh, N. (Osaka Prefectural Univ., Sakai (Japan)), Aoki, M, Shimada, T, Akiyoshi, H, Hassanin, A, Ohashi, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Agonists - administration & dosage Adrenergic alpha-Agonists - pharmacology ANAESTHESIA ANALGESICS anesthesia Anesthetics, Inhalation - administration & dosage Anesthetics, Inhalation - pharmacology Animals Blood Pressure - drug effects canine Diuresis - drug effects DOGS Dogs - physiology Dose-Response Relationship, Drug Drug Administration Schedule - veterinary Drug Interactions Glomerular Filtration Rate - drug effects Glomerular Filtration Rate - veterinary Injections, Intramuscular - veterinary Injections, Intravenous - veterinary isoflurane Isoflurane - administration & dosage Isoflurane - pharmacology Kidney - drug effects KIDNEYS Male Medetomidine - administration & dosage Medetomidine - pharmacology medetomidine and renal function
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