Simulation and fabrication of capillary-driven meander micromixer for short-distance mixing
In recent years, the emerging bio-chip technology has used external powered pumps for fluidic pumping and mixing. The short-term capillary-driven micromixers with complex mixing structures also showed large potential for mixing devices. This reported work demonstrates the long-term capillary-driven...
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| Veröffentlicht in: | Micro & nano letters 2013-10, Vol.8 (10), p.567-570 |
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| creator | Chung, C.-K Lai, C.C Shih, T.R Chang, E.C Chen, S.W |
| description | In recent years, the emerging bio-chip technology has used external powered pumps for fluidic pumping and mixing. The short-term capillary-driven micromixers with complex mixing structures also showed large potential for mixing devices. This reported work demonstrates the long-term capillary-driven meander micromixer with the planar design, short mixing distance and power-free rapid fluid, transport functions which is compared with conventional syringe pump micormixers. The surface property of various materials was verified by contact angle measurement. Both intrinsic hydrophilic materials of glass and JSR photoresist were good candidates and selected for fabricating the capillary-driven meander micromixer using simple photolithography, laser ablation and low-temperature bonding technology without chemical etching and without the deposition process. The design and simulation of such an effective capillary-driven micromixer have been performed for understanding the geometry effect on flow and mixing behaviour. The glass–JSR–glass capillary-driven meander micromixer can improve mixing efficiency up to over 95% at a short distance of only 8 mm, and has potential for the application of power-free microfluidic chip fabrication and bio-medical examination in the future. |
| doi_str_mv | 10.1049/mnl.2013.0329 |
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The short-term capillary-driven micromixers with complex mixing structures also showed large potential for mixing devices. This reported work demonstrates the long-term capillary-driven meander micromixer with the planar design, short mixing distance and power-free rapid fluid, transport functions which is compared with conventional syringe pump micormixers. The surface property of various materials was verified by contact angle measurement. Both intrinsic hydrophilic materials of glass and JSR photoresist were good candidates and selected for fabricating the capillary-driven meander micromixer using simple photolithography, laser ablation and low-temperature bonding technology without chemical etching and without the deposition process. The design and simulation of such an effective capillary-driven micromixer have been performed for understanding the geometry effect on flow and mixing behaviour. The glass–JSR–glass capillary-driven meander micromixer can improve mixing efficiency up to over 95% at a short distance of only 8 mm, and has potential for the application of power-free microfluidic chip fabrication and bio-medical examination in the future.</description><identifier>ISSN: 1750-0443</identifier><identifier>EISSN: 1750-0443</identifier><identifier>DOI: 10.1049/mnl.2013.0329</identifier><language>eng</language><publisher>Stevenage: The Institution of Engineering and Technology</publisher><subject>biochip technology ; biomedical equipment ; biomedical examination ; biomedical measurement ; bioMEMS ; complex mixing structures ; Contact angle ; Devices ; effective capillary‐driven micromixer ; external powered pumps ; flow behaviour ; fluidic mixing ; fluidic pumping ; geometry effect ; glass ; glass‐JSR‐glass capillary‐driven meander micromixer ; hydrophilicity ; intrinsic hydrophilic materials ; JSR photoresist ; lab‐on‐a‐chip ; laser ablation ; long‐term capillary‐driven meander micromixer ; low‐temperature bonding technology ; Materials selection ; Meanders ; microfabrication ; Microfluidics ; mixing ; mixing behaviour ; mixing devices ; Nanostructure ; photolithography ; photoresists ; power‐free microfluidic chip fabrication ; power‐free rapid fluid ; Pumps ; short‐distance mixing ; short‐term capillary‐driven micromixers ; Simulation ; Special Section: Expanded Papers from NEMS 2013 ; surface property ; transport functions</subject><ispartof>Micro & nano letters, 2013-10, Vol.8 (10), p.567-570</ispartof><rights>The Institution of Engineering and Technology</rights><rights>2013 The Institution of Engineering and Technology</rights><rights>Copyright The Institution of Engineering & Technology Oct 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4487-d9b6d554caf818d3e58f54ceb0728dfa3072a7bc84c9720a41c895a6e4a0b7e03</citedby><cites>FETCH-LOGICAL-c4487-d9b6d554caf818d3e58f54ceb0728dfa3072a7bc84c9720a41c895a6e4a0b7e03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1049%2Fmnl.2013.0329$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1049%2Fmnl.2013.0329$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,11561,27923,27924,45573,45574,46051,46475</link.rule.ids><linktorsrc>$$Uhttps://onlinelibrary.wiley.com/doi/abs/10.1049%2Fmnl.2013.0329$$EView_record_in_Wiley-Blackwell$$FView_record_in_$$GWiley-Blackwell</linktorsrc></links><search><creatorcontrib>Chung, C.-K</creatorcontrib><creatorcontrib>Lai, C.C</creatorcontrib><creatorcontrib>Shih, T.R</creatorcontrib><creatorcontrib>Chang, E.C</creatorcontrib><creatorcontrib>Chen, S.W</creatorcontrib><title>Simulation and fabrication of capillary-driven meander micromixer for short-distance mixing</title><title>Micro & nano letters</title><description>In recent years, the emerging bio-chip technology has used external powered pumps for fluidic pumping and mixing. The short-term capillary-driven micromixers with complex mixing structures also showed large potential for mixing devices. This reported work demonstrates the long-term capillary-driven meander micromixer with the planar design, short mixing distance and power-free rapid fluid, transport functions which is compared with conventional syringe pump micormixers. The surface property of various materials was verified by contact angle measurement. Both intrinsic hydrophilic materials of glass and JSR photoresist were good candidates and selected for fabricating the capillary-driven meander micromixer using simple photolithography, laser ablation and low-temperature bonding technology without chemical etching and without the deposition process. The design and simulation of such an effective capillary-driven micromixer have been performed for understanding the geometry effect on flow and mixing behaviour. The glass–JSR–glass capillary-driven meander micromixer can improve mixing efficiency up to over 95% at a short distance of only 8 mm, and has potential for the application of power-free microfluidic chip fabrication and bio-medical examination in the future.</description><subject>biochip technology</subject><subject>biomedical equipment</subject><subject>biomedical examination</subject><subject>biomedical measurement</subject><subject>bioMEMS</subject><subject>complex mixing structures</subject><subject>Contact angle</subject><subject>Devices</subject><subject>effective capillary‐driven micromixer</subject><subject>external powered pumps</subject><subject>flow behaviour</subject><subject>fluidic mixing</subject><subject>fluidic pumping</subject><subject>geometry effect</subject><subject>glass</subject><subject>glass‐JSR‐glass capillary‐driven meander micromixer</subject><subject>hydrophilicity</subject><subject>intrinsic hydrophilic materials</subject><subject>JSR photoresist</subject><subject>lab‐on‐a‐chip</subject><subject>laser ablation</subject><subject>long‐term capillary‐driven meander micromixer</subject><subject>low‐temperature bonding technology</subject><subject>Materials selection</subject><subject>Meanders</subject><subject>microfabrication</subject><subject>Microfluidics</subject><subject>mixing</subject><subject>mixing behaviour</subject><subject>mixing devices</subject><subject>Nanostructure</subject><subject>photolithography</subject><subject>photoresists</subject><subject>power‐free microfluidic chip fabrication</subject><subject>power‐free rapid fluid</subject><subject>Pumps</subject><subject>short‐distance mixing</subject><subject>short‐term capillary‐driven micromixers</subject><subject>Simulation</subject><subject>Special Section: Expanded Papers from NEMS 2013</subject><subject>surface property</subject><subject>transport functions</subject><issn>1750-0443</issn><issn>1750-0443</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNp9kL1PwzAQxS0EEqUwskdCSDCk2LETJ2OpKCC1ZQAmBsvxB7jKF3YC7X-PozBUCJjuTv7d87sHwCmCEwRJdlVWxSSCCE8gjrI9MEI0hiEkBO_v9IfgyLk1hIRGNBuBl0dTdgVvTV0FvJKB5rk1YphrHQjemKLgdhtKaz5UFZTKU8oGpRG2Ls3Gt7q2gXurbRtK41peCeVfN6Z6PQYHmhdOnXzXMXie3zzN7sLFw-39bLoIBSEpDWWWJzKOieA6RanEKk61n1QOaZRKzbGvnOYiJSKjEeQEiTSLeaIIhzlVEI_BxaDb2Pq9U65lpXFCed-VqjvHUIwwoRnJYo-e_UDXdWcr744hkqQkxpj2guFA-Ruds0qzxprSp8AQZH3UzEfN-qhZH7Xnk4H_NIXa_g-z5WoaXc8h9Gf5xcth0ahdJ398cv4Lu1wtdrQbqfEXxI-cHg</recordid><startdate>201310</startdate><enddate>201310</enddate><creator>Chung, C.-K</creator><creator>Lai, C.C</creator><creator>Shih, T.R</creator><creator>Chang, E.C</creator><creator>Chen, S.W</creator><general>The Institution of Engineering and Technology</general><general>John Wiley & Sons, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7TB</scope><scope>7U5</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>F28</scope><scope>FR3</scope><scope>HCIFZ</scope><scope>KB.</scope><scope>L6V</scope><scope>L7M</scope><scope>M7S</scope><scope>P5Z</scope><scope>P62</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>S0W</scope></search><sort><creationdate>201310</creationdate><title>Simulation and fabrication of capillary-driven meander micromixer for short-distance mixing</title><author>Chung, C.-K ; Lai, C.C ; Shih, T.R ; Chang, E.C ; Chen, S.W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4487-d9b6d554caf818d3e58f54ceb0728dfa3072a7bc84c9720a41c895a6e4a0b7e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>biochip technology</topic><topic>biomedical equipment</topic><topic>biomedical examination</topic><topic>biomedical measurement</topic><topic>bioMEMS</topic><topic>complex mixing structures</topic><topic>Contact angle</topic><topic>Devices</topic><topic>effective capillary‐driven micromixer</topic><topic>external powered pumps</topic><topic>flow behaviour</topic><topic>fluidic mixing</topic><topic>fluidic pumping</topic><topic>geometry effect</topic><topic>glass</topic><topic>glass‐JSR‐glass capillary‐driven meander micromixer</topic><topic>hydrophilicity</topic><topic>intrinsic hydrophilic materials</topic><topic>JSR photoresist</topic><topic>lab‐on‐a‐chip</topic><topic>laser ablation</topic><topic>long‐term capillary‐driven meander micromixer</topic><topic>low‐temperature bonding technology</topic><topic>Materials selection</topic><topic>Meanders</topic><topic>microfabrication</topic><topic>Microfluidics</topic><topic>mixing</topic><topic>mixing behaviour</topic><topic>mixing devices</topic><topic>Nanostructure</topic><topic>photolithography</topic><topic>photoresists</topic><topic>power‐free microfluidic chip fabrication</topic><topic>power‐free rapid fluid</topic><topic>Pumps</topic><topic>short‐distance mixing</topic><topic>short‐term capillary‐driven micromixers</topic><topic>Simulation</topic><topic>Special Section: Expanded Papers from NEMS 2013</topic><topic>surface property</topic><topic>transport functions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chung, C.-K</creatorcontrib><creatorcontrib>Lai, C.C</creatorcontrib><creatorcontrib>Shih, T.R</creatorcontrib><creatorcontrib>Chang, E.C</creatorcontrib><creatorcontrib>Chen, S.W</creatorcontrib><collection>CrossRef</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection (ProQuest)</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>SciTech Premium Collection</collection><collection>Materials Science Database</collection><collection>ProQuest Engineering Collection</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Engineering Database</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Materials Science Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>DELNET Engineering & Technology Collection</collection><jtitle>Micro & nano letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Chung, C.-K</au><au>Lai, C.C</au><au>Shih, T.R</au><au>Chang, E.C</au><au>Chen, S.W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Simulation and fabrication of capillary-driven meander micromixer for short-distance mixing</atitle><jtitle>Micro & nano letters</jtitle><date>2013-10</date><risdate>2013</risdate><volume>8</volume><issue>10</issue><spage>567</spage><epage>570</epage><pages>567-570</pages><issn>1750-0443</issn><eissn>1750-0443</eissn><abstract>In recent years, the emerging bio-chip technology has used external powered pumps for fluidic pumping and mixing. The short-term capillary-driven micromixers with complex mixing structures also showed large potential for mixing devices. This reported work demonstrates the long-term capillary-driven meander micromixer with the planar design, short mixing distance and power-free rapid fluid, transport functions which is compared with conventional syringe pump micormixers. The surface property of various materials was verified by contact angle measurement. Both intrinsic hydrophilic materials of glass and JSR photoresist were good candidates and selected for fabricating the capillary-driven meander micromixer using simple photolithography, laser ablation and low-temperature bonding technology without chemical etching and without the deposition process. The design and simulation of such an effective capillary-driven micromixer have been performed for understanding the geometry effect on flow and mixing behaviour. The glass–JSR–glass capillary-driven meander micromixer can improve mixing efficiency up to over 95% at a short distance of only 8 mm, and has potential for the application of power-free microfluidic chip fabrication and bio-medical examination in the future.</abstract><cop>Stevenage</cop><pub>The Institution of Engineering and Technology</pub><doi>10.1049/mnl.2013.0329</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | biochip technology biomedical equipment biomedical examination biomedical measurement bioMEMS complex mixing structures Contact angle Devices effective capillary‐driven micromixer external powered pumps flow behaviour fluidic mixing fluidic pumping geometry effect glass glass‐JSR‐glass capillary‐driven meander micromixer hydrophilicity intrinsic hydrophilic materials JSR photoresist lab‐on‐a‐chip laser ablation long‐term capillary‐driven meander micromixer low‐temperature bonding technology Materials selection Meanders microfabrication Microfluidics mixing mixing behaviour mixing devices Nanostructure photolithography photoresists power‐free microfluidic chip fabrication power‐free rapid fluid Pumps short‐distance mixing short‐term capillary‐driven micromixers Simulation Special Section: Expanded Papers from NEMS 2013 surface property transport functions |
| title | Simulation and fabrication of capillary-driven meander micromixer for short-distance mixing |
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