Hypospadias and Incomplete Preputial Separation in Male Rats Induced by Prenatal Exposure to an Anti-androgen, Flutamide

Hypospadias was induced in male Sprague-Dawley rats by prenatal exposure to 30 mg/kg/day of flutamide from gestational days 14 to 17, or from 18 to 21. Their external genitalia were examined histopathologically and compared to untreated controls. On postnatal day 6, the glans penis of untreated cont...

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Veröffentlicht in:	Journal of Toxicologic Pathology 2004, Vol.17(2), pp.113-118
Hauptverfasser:	Yoshimura, Shinsuke, Yamaguchi, Hajime, Konno, Kazunori, Ohsawa, Noriko, Noguchi, Satoshi, Chisaka, Akiko
Format:	Artikel
Sprache:	eng
Schlagworte:	anti-androgen flutamide hypospadias prenatal exposure rat
Online-Zugang:	Volltext
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